PMID- 29119493
OWN - NLM
STAT- MEDLINE
DCOM- 20181107
LR  - 20181113
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 25
IP  - 3
DP  - 2018 Jan
TI  - Liquid chromatography-mass spectrometry method for evaluating the dissipation 
      dynamics of cyromazine and its metabolite in Agaricus bisporus and dietary risk 
      assessment.
PG  - 2285-2292
LID - 10.1007/s11356-017-0658-y [doi]
AB  - Providing guidance on the reasonable use of pesticide in agricultural production 
      is of particular importance for ensuring food safety. In the present study, a 
      field trial was performed to study the dissipation and accumulative pattern of 
      cyromazine (CA) and its metabolite in Agaricus bisporus (A. bisporus) 
      cultivation. An ultra-performance liquid chromatography-tandem mass spectrometry 
      (UPLC-MS/MS) method was first developed and validated for the determination of CA 
      and melamine (MEL) in the casing soil and fruiting body. During the cultivation 
      period, the dissipation rates of CA in the casing soil were between 51.57 and 
      63.48% at three dose groups. The fruiting body presented higher accumulation 
      ability for MEL compared with CA. The terminal residues of MEL never exceeded the 
      maximum residue limits (MRLs) in food. In addition, the intake health risk from 
      the CA and MEL residues in the fruiting body were negligible to humans. This 
      study will help to provide valuable guidance on the application strategies of CA 
      in A. bisporus cultivation.
FAU - Zhao, Zhiyong
AU  - Zhao Z
AD  - Institute for Agro-food Standards and Testing Technology, Laboratory of Quality & 
      Safety Risk Assessment for Agro-products (Shanghai), Ministry of Agriculture, 
      Shanghai Academy of Agricultural Sciences, 1000 Jinqi Road, Shanghai, 201403, 
      People's Republic of China.
FAU - Chen, Lei
AU  - Chen L
AD  - Institute for Agro-food Standards and Testing Technology, Laboratory of Quality & 
      Safety Risk Assessment for Agro-products (Shanghai), Ministry of Agriculture, 
      Shanghai Academy of Agricultural Sciences, 1000 Jinqi Road, Shanghai, 201403, 
      People's Republic of China.
FAU - Bai, Bing
AU  - Bai B
AD  - Institute for Agro-food Standards and Testing Technology, Laboratory of Quality & 
      Safety Risk Assessment for Agro-products (Shanghai), Ministry of Agriculture, 
      Shanghai Academy of Agricultural Sciences, 1000 Jinqi Road, Shanghai, 201403, 
      People's Republic of China.
FAU - Yang, Xianli
AU  - Yang X
AD  - Institute for Agro-food Standards and Testing Technology, Laboratory of Quality & 
      Safety Risk Assessment for Agro-products (Shanghai), Ministry of Agriculture, 
      Shanghai Academy of Agricultural Sciences, 1000 Jinqi Road, Shanghai, 201403, 
      People's Republic of China.
FAU - Tan, Yanglan
AU  - Tan Y
AD  - Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, 
      Chinese Academy of Sciences, Shanghai, 200031, China.
FAU - Wang, Jianhua
AU  - Wang J
AD  - Institute for Agro-food Standards and Testing Technology, Laboratory of Quality & 
      Safety Risk Assessment for Agro-products (Shanghai), Ministry of Agriculture, 
      Shanghai Academy of Agricultural Sciences, 1000 Jinqi Road, Shanghai, 201403, 
      People's Republic of China.
FAU - Zhao, Xiaoyan
AU  - Zhao X
AD  - Institute for Agro-food Standards and Testing Technology, Laboratory of Quality & 
      Safety Risk Assessment for Agro-products (Shanghai), Ministry of Agriculture, 
      Shanghai Academy of Agricultural Sciences, 1000 Jinqi Road, Shanghai, 201403, 
      People's Republic of China. cindy8119@163.com.
FAU - Zhou, Changyan
AU  - Zhou C
AD  - Institute for Agro-food Standards and Testing Technology, Laboratory of Quality & 
      Safety Risk Assessment for Agro-products (Shanghai), Ministry of Agriculture, 
      Shanghai Academy of Agricultural Sciences, 1000 Jinqi Road, Shanghai, 201403, 
      People's Republic of China. changyanz@sina.com.
LA  - eng
GR  - GJFP2017006/National Major Project for Agro-product Quality & Safety Risk 
      Assessment/
GR  - 31602124/National Natural Science Foundation of China (CN)/
GR  - G20160502/Shanghai Agriculture Applied Technology Development Program, China/
PT  - Journal Article
DEP - 20171108
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Pesticide Residues)
RN  - 0 (Soil)
RN  - 0 (Triazines)
RN  - CA49Y29RA9 (cyromazine)
RN  - N3GP2YSD88 (melamine)
SB  - IM
MH  - Agaricus/*chemistry/metabolism
MH  - Chromatography, High Pressure Liquid/methods
MH  - Dietary Exposure/*analysis
MH  - Fruiting Bodies, Fungal/*chemistry/metabolism
MH  - Humans
MH  - Pesticide Residues/*analysis/metabolism
MH  - Risk Assessment
MH  - Soil/chemistry
MH  - Tandem Mass Spectrometry/methods
MH  - Triazines/*analysis/metabolism
OTO - NOTNLM
OT  - Agaricus bisporus
OT  - Bioconcentration
OT  - Cyromazine and melamine
OT  - Dietary risk assessment
OT  - Dissipation
EDAT- 2017/11/10 06:00
MHDA- 2018/11/08 06:00
CRDT- 2017/11/10 06:00
PHST- 2017/06/24 00:00 [received]
PHST- 2017/10/31 00:00 [accepted]
PHST- 2017/11/10 06:00 [pubmed]
PHST- 2018/11/08 06:00 [medline]
PHST- 2017/11/10 06:00 [entrez]
AID - 10.1007/s11356-017-0658-y [pii]
AID - 10.1007/s11356-017-0658-y [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2018 Jan;25(3):2285-2292. doi: 
      10.1007/s11356-017-0658-y. Epub 2017 Nov 8.