PMID- 29121358
OWN - NLM
STAT- MEDLINE
DCOM- 20171127
LR  - 20201209
IS  - 2325-8179 (Electronic)
IS  - 2325-8160 (Linking)
VI  - 48
IP  - 11
DP  - 2017 Nov 1
TI  - Optical Coherence Tomography Findings in Endogenous Fungal Chorioretinitis, 
      Retinitis, and Endophthalmitis.
PG  - 894-901
LID - 10.3928/23258160-20171030-04 [doi]
AB  - BACKGROUND AND OBJECTIVE: To describe spectral-domain optical coherence 
      tomography (SD-OCT) findings in eyes with endogenous fungal chorioretinitis and 
      endophthalmitis. PATIENTS AND METHODS: Retrospective, observational case series 
      of subjects at Wills Eye Hospital and William Beaumont Hospital were identified 
      by screening OCT billing data and cross-referencing with patient charts. Clinical 
      and imaging data were collected for each patient and reviewed. RESULTS: Twelve 
      eyes of seven consecutive patients were identified, demonstrating two patterns of 
      posterior ocular involvement: chorioretinal infiltration and superficial 
      retinal/retinal vascular infiltration without choroidal involvement. Six of 12 
      eyes had follow-up imaging performed after antifungal treatment, which 
      demonstrated decreased size of choroidal and/or retinal infiltrates. CONCLUSIONS: 
      All patients with follow-up imaging had anatomic improvement by OCT of the 
      lesions with treatment. In the future, OCT imaging may provide a method to assess 
      therapeutic response and prognosis for visual recovery in patients with 
      endogenous fungal ocular disease. [Ophthalmic Surg Lasers Imaging Retina. 
      2017;48:894-901.].
CI  - Copyright 2017, SLACK Incorporated.
FAU - Stephens, John D
AU  - Stephens JD
FAU - Adam, Murtaza K
AU  - Adam MK
FAU - Todorich, Bohzo
AU  - Todorich B
FAU - Faia, Lisa J
AU  - Faia LJ
FAU - Garg, Sunir
AU  - Garg S
FAU - Dunn, James P
AU  - Dunn JP
FAU - Mehta, Sonia
AU  - Mehta S
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
PL  - United States
TA  - Ophthalmic Surg Lasers Imaging Retina
JT  - Ophthalmic surgery, lasers & imaging retina
JID - 101599215
RN  - 0 (Antifungal Agents)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Antifungal Agents/therapeutic use
MH  - Candida albicans/isolation & purification
MH  - Candidiasis/*diagnosis/drug therapy/microbiology
MH  - Chorioretinitis/*diagnosis/drug therapy/microbiology
MH  - Endophthalmitis/*diagnosis/drug therapy/microbiology
MH  - Eye Infections, Fungal/*diagnosis/drug therapy/microbiology
MH  - Female
MH  - Fluorescein Angiography
MH  - Fungemia/diagnosis
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retinitis/*diagnosis/drug therapy/microbiology
MH  - Retrospective Studies
MH  - *Tomography, Optical Coherence
MH  - Visual Acuity/physiology
EDAT- 2017/11/10 06:00
MHDA- 2017/11/29 06:00
CRDT- 2017/11/10 06:00
PHST- 2017/02/14 00:00 [received]
PHST- 2017/06/02 00:00 [accepted]
PHST- 2017/11/10 06:00 [entrez]
PHST- 2017/11/10 06:00 [pubmed]
PHST- 2017/11/29 06:00 [medline]
AID - 10.3928/23258160-20171030-04 [doi]
PST - ppublish
SO  - Ophthalmic Surg Lasers Imaging Retina. 2017 Nov 1;48(11):894-901. doi: 
      10.3928/23258160-20171030-04.