PMID- 29121620 OWN - NLM STAT- MEDLINE DCOM- 20171128 LR - 20171128 IS - 1175-8716 (Electronic) IS - 0028-8446 (Linking) VI - 130 IP - 1465 DP - 2017 Nov 10 TI - Dispensing patterns for antidiabetic agents in New Zealand: are the guidelines being followed? PG - 12-18 AB - AIMS: Type 2 diabetes mellitus (T2DM) is a significant public health issue in New Zealand. Effective management and glycaemic control is critical for reducing diabetes-related complications. Treatment guidelines are well established in New Zealand. Using dispensing data as a proxy for prescribing data, this paper aims to describe the pattern of first- and second-line antidiabetic agent (AA) dispensing for T2DM in New Zealand and assess adherence with treatment guidelines. METHODS: Analysis of national dispensing data for AA medications using the Pharmaceutical Collection database from 2007/08 to 2015/16. RESULTS: Metformin monotherapy remains the most commonly prescribed first-line T2DM medication prescribed, accounting for 85% of initial agents prescribed. Sulfonylureas are the most common second-line agents used, accounting for 70% of all second-line agents. CONCLUSION: There is a high degree of adherence with the T2DM treatment guidelines in New Zealand. FAU - Murray, Peter AU - Murray P AD - Medical Directorate, PHARMAC, Wellington. FAU - Norris, Hew AU - Norris H AD - Analysis, Corporate Directorate, PHARMAC, Wellington. FAU - Metcalfe, Scott AU - Metcalfe S AD - Medical Directorate, PHARMAC, Wellington. FAU - Betty, Bryan AU - Betty B AD - Medical Directorate, PHARMAC, Wellington. FAU - Young, Vanessa AU - Young V AD - Operations Directorate, PHARMAC, Wellington. FAU - Locke, Bronwyn AU - Locke B AD - Engagement and Implementation Directorate, PHARMAC, Wellington. LA - eng PT - Journal Article DEP - 20171110 PL - New Zealand TA - N Z Med J JT - The New Zealand medical journal JID - 0401067 RN - 0 (Blood Glucose) RN - 0 (Hypoglycemic Agents) RN - 9100L32L2N (Metformin) SB - IM CIN - N Z Med J. 2017 Nov 10;130(1465):9-11. PMID: 29121619 MH - Blood Glucose MH - Diabetes Mellitus, Type 2/*drug therapy/epidemiology MH - Humans MH - Hypoglycemic Agents/*therapeutic use MH - Medication Adherence/*statistics & numerical data MH - Metformin/therapeutic use MH - New Zealand COIS- The authors are (or were at the time of writing) employees of PHARMAC; the views expressed do not necessarily represent those of PHARMAC. EDAT- 2017/11/10 06:00 MHDA- 2017/11/29 06:00 CRDT- 2017/11/10 06:00 PHST- 2017/11/10 06:00 [entrez] PHST- 2017/11/10 06:00 [pubmed] PHST- 2017/11/29 06:00 [medline] PST - epublish SO - N Z Med J. 2017 Nov 10;130(1465):12-18.