PMID- 29122234
OWN - NLM
STAT- MEDLINE
DCOM- 20180622
LR  - 20180622
IS  - 0034-7450 (Print)
IS  - 0034-7450 (Linking)
VI  - 46
IP  - 4
DP  - 2017 Oct-Dec
TI  - [Suspicion Index: Psychiatric Manifestations of NMDAR Encephalitis in Paediatric 
      Patients].
PG  - 252-256
LID - S0034-7450(16)30110-X [pii]
LID - 10.1016/j.rcp.2016.10.002 [doi]
AB  - Immune encephalitis is a diverse group of disorders that share some unique 
      diagnostic approaches and specific treatments. Some of the initial manifestations 
      are non-specific and difficult to distinguish from encephalitis of other 
      aetiologies, and even with modern diagnostic tools there are still a number of 
      cases for which definitive causes cannot be clarified. Among these, 
      N-methyl-D-aspartate receptor (NMDAR) encephalitis is a particular form of immune 
      encephalitis that has some distinctive clinical manifestations, which allows the 
      clinical evaluator to suggest a more accurate diagnosis and start treatments even 
      in the absence of specific laboratory tests. Three paediatric patients, who were 
      treated for NMDAR encephalitis are described in this article, as well as 
      comparing their clinical presentation. This specific disorder and some of the 
      more relevant features of its physiopathology are reviewed in order to explain 
      the initial psychiatric manifestations, for which early recognition is critical 
      for an appropriate diagnosis and treatment.
CI  - Copyright (c) 2016 Asociacion Colombiana de Psiquiatria. Publicado por Elsevier 
      Espana. All rights reserved.
FAU - Gomez Castro, Juan Fernando
AU  - Gomez Castro JF
AD  - Departamento Materno-Infantil, Fundacion Valle del Lili, Universidad ICESI, Cali, 
      Colombia. Electronic address: jfgomezcastro@gmail.com.
FAU - Salazar, Omar
AU  - Salazar O
AD  - Departamento de Psiquiatria, Fundacion Valle del Lili, Universidad ICESI, Cali, 
      Colombia.
FAU - Conde, Zenayda
AU  - Conde Z
AD  - Departamento de Psiquiatria, Fundacion Valle del Lili, Universidad ICESI, Cali, 
      Colombia.
LA  - spa
PT  - Case Reports
PT  - Journal Article
TT  - Indice de sospecha: manifestaciones psiquiatricas de la encefalitis por 
      anticuerpos anti-NMDAR en pacientes pediatricos.
DEP - 20161117
PL  - Colombia
TA  - Rev Colomb Psiquiatr
JT  - Revista colombiana de psiquiatria
JID - 0045130
SB  - IM
MH  - Anti-N-Methyl-D-Aspartate Receptor 
      Encephalitis/*diagnosis/physiopathology/psychology
MH  - Child
MH  - Child, Preschool
MH  - Diagnosis, Differential
MH  - Early Diagnosis
MH  - Encephalitis/*diagnosis
MH  - Female
MH  - Humans
MH  - Male
OTO - NOTNLM
OT  - Encefalitis
OT  - Encephalitis
OT  - Manifestaciones psiquiatricas
OT  - NMDAR
OT  - Psychiatric manifestations
OT  - Receptor NMDAr
EDAT- 2017/11/11 06:00
MHDA- 2018/06/23 06:00
CRDT- 2017/11/11 06:00
PHST- 2016/07/02 00:00 [received]
PHST- 2016/09/18 00:00 [revised]
PHST- 2016/10/13 00:00 [accepted]
PHST- 2017/11/11 06:00 [entrez]
PHST- 2017/11/11 06:00 [pubmed]
PHST- 2018/06/23 06:00 [medline]
AID - S0034-7450(16)30110-X [pii]
AID - 10.1016/j.rcp.2016.10.002 [doi]
PST - ppublish
SO  - Rev Colomb Psiquiatr. 2017 Oct-Dec;46(4):252-256. doi: 10.1016/j.rcp.2016.10.002. 
      Epub 2016 Nov 17.