PMID- 29124979
OWN - NLM
STAT- MEDLINE
DCOM- 20180625
LR  - 20220205
IS  - 1521-0464 (Electronic)
IS  - 1071-7544 (Print)
IS  - 1071-7544 (Linking)
VI  - 24
IP  - sup1
DP  - 2017
TI  - Mesoporous carbon nanomaterials in drug delivery and biomedical application.
PG  - 94-107
LID - 10.1080/10717544.2017.1399300 [doi]
AB  - Recent development of nano-technology provides highly efficient and versatile 
      treatment methods to achieve better therapeutic efficacy and lower side effects 
      of malignant cancer. The exploration of drug delivery systems (DDSs) based on 
      nano-material shows great promise in translating nano-technology to clinical use 
      to benefit patients. As an emerging inorganic nanomaterial, mesoporous carbon 
      nanomaterials (MCNs) possess both the mesoporous structure and the carbonaceous 
      composition, endowing them with superior nature compared with mesoporous silica 
      nanomaterials and other carbon-based materials, such as carbon nanotube, graphene 
      and fullerene. In this review, we highlighted the cutting-edge progress of carbon 
      nanomaterials as drug delivery systems (DDSs), including immediate/sustained drug 
      delivery systems and controlled/targeted drug delivery systems. In addition, 
      several representative biomedical applications of mesoporous carbon such as (1) 
      photo-chemo synergistic therapy; (2) delivery of therapeutic biomolecule and (3) 
      in vivo bioimaging are discussed and integrated. Finally, potential challenges 
      and outlook for future development of mesoporous carbon in biomedical fields have 
      been discussed in detail.
FAU - Zhao, Qinfu
AU  - Zhao Q
AD  - a Department of Pharmaceutics , School of Pharmacy, Shenyang Pharmaceutical 
      University , Shenyang , PR China.
FAU - Lin, Yuanzhe
AU  - Lin Y
AD  - a Department of Pharmaceutics , School of Pharmacy, Shenyang Pharmaceutical 
      University , Shenyang , PR China.
FAU - Han, Ning
AU  - Han N
AD  - b School of Chinese Materia Medica, Department of Chinese Medicinal Pharmaceutics 
      , Beijing university of Chinese Medicine , Beijing , PR China.
FAU - Li, Xian
AU  - Li X
AD  - a Department of Pharmaceutics , School of Pharmacy, Shenyang Pharmaceutical 
      University , Shenyang , PR China.
FAU - Geng, Hongjian
AU  - Geng H
AD  - a Department of Pharmaceutics , School of Pharmacy, Shenyang Pharmaceutical 
      University , Shenyang , PR China.
FAU - Wang, Xiudan
AU  - Wang X
AD  - a Department of Pharmaceutics , School of Pharmacy, Shenyang Pharmaceutical 
      University , Shenyang , PR China.
FAU - Cui, Yu
AU  - Cui Y
AD  - a Department of Pharmaceutics , School of Pharmacy, Shenyang Pharmaceutical 
      University , Shenyang , PR China.
FAU - Wang, Siling
AU  - Wang S
AD  - a Department of Pharmaceutics , School of Pharmacy, Shenyang Pharmaceutical 
      University , Shenyang , PR China.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Drug Deliv
JT  - Drug delivery
JID - 9417471
RN  - 7440-44-0 (Carbon)
RN  - 7631-86-9 (Silicon Dioxide)
RN  - 7782-42-5 (Graphite)
SB  - IM
MH  - Animals
MH  - Carbon/*chemistry
MH  - Drug Delivery Systems/methods
MH  - Graphite/chemistry
MH  - Humans
MH  - Nanoparticles/chemistry
MH  - Nanostructures/*chemistry
MH  - Porosity
MH  - Silicon Dioxide/chemistry
PMC - PMC8812584
OTO - NOTNLM
OT  - Mesoporous carbon nanomaterials
OT  - biocompatibility
OT  - biomedical applications
OT  - drug delivery systems
OT  - photothermal therapy
COIS- The authors report no conflicts of interest.
EDAT- 2017/11/11 06:00
MHDA- 2018/06/26 06:00
PMCR- 2017/11/10
CRDT- 2017/11/11 06:00
PHST- 2017/11/11 06:00 [entrez]
PHST- 2017/11/11 06:00 [pubmed]
PHST- 2018/06/26 06:00 [medline]
PHST- 2017/11/10 00:00 [pmc-release]
AID - 1399300 [pii]
AID - 10.1080/10717544.2017.1399300 [doi]
PST - ppublish
SO  - Drug Deliv. 2017;24(sup1):94-107. doi: 10.1080/10717544.2017.1399300.