PMID- 29126338
OWN - NLM
STAT- MEDLINE
DCOM- 20180404
LR  - 20190308
IS  - 1439-3964 (Electronic)
IS  - 0172-4622 (Linking)
VI  - 39
IP  - 1
DP  - 2018 Jan
TI  - Effect of Neuromuscular Electrical Stimulation on Brain-derived Neurotrophic 
      Factor.
PG  - 5-11
LID - 10.1055/s-0043-120343 [doi]
AB  - Brain-derived neurotrophic factor (BDNF) has been considered an essential 
      mediator responsible for the beneficial effects of physical activity in 
      preventing cognitive impairment. This study aimed at examining the effects of a 
      single bout of neuromuscular electrical stimulation (NMES) on levels of BDNF in 
      the plasma and on cognitive performance in healthy adult men. Thirteen healthy 
      adult men participated in three experimental sessions. The first session was 
      30 min of NMES to both legs, the second was 30 min of cycling exercise at the 
      intensity of 60% peak oxygen uptake, and the third was 30 min of complete rest. 
      Blood was examined for plasma BDNF levels and glucose concentrations, and 
      cognitive performance tests were performed before and after each session. A 
      single bout of NMES significantly increased plasma BDNF levels (p<0.05), which 
      were equivalent to the amount of plasma BDNF released during the exercise session 
      (p>0.05). However, there were no significant changes in cognitive performance 
      between the sessions (p>0.05). The present study found that a single bout of NMES 
      significantly increased plasma BDNF to levels normally present during moderate 
      voluntary exercise. Therefore, NMES could serve as an alternative method of 
      exercise, and might shed light on individuals for whom voluntary physical 
      exercise is contraindicated.
CI  - (c) Georg Thieme Verlag KG Stuttgart . New York.
FAU - Miyamoto, Toshiaki
AU  - Miyamoto T
AD  - School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan.
FAU - Kou, Keihou
AU  - Kou K
AD  - School of Nursing, Hyogo University of Health Sciences, Kobe, Japan.
FAU - Yanamoto, Hideya
AU  - Yanamoto H
AD  - School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan.
FAU - Hashimoto, Saya
AU  - Hashimoto S
AD  - School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan.
FAU - Ikawa, Mai
AU  - Ikawa M
AD  - School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan.
FAU - Sekiyama, Takashi
AU  - Sekiyama T
AD  - School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan.
FAU - Nakano, Yoshiki
AU  - Nakano Y
AD  - School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan.
FAU - Kashiwamura, Shin-Ichiro
AU  - Kashiwamura SI
AD  - General Education Center, Hyogo University of Health Sciences, Kobe, Japan.
AD  - Institute for Advanced Medical Sciences, Hyogo College of Medicine Nishinomiya, 
      Japan.
FAU - Takeda, Chisako
AU  - Takeda C
AD  - School of Nursing, Hyogo University of Health Sciences, Kobe, Japan.
FAU - Fujioka, Hiroyuki
AU  - Fujioka H
AD  - School of Rehabilitation, Hyogo University of Health Sciences, Kobe, Japan.
LA  - eng
PT  - Journal Article
DEP - 20171110
PL  - Germany
TA  - Int J Sports Med
JT  - International journal of sports medicine
JID - 8008349
RN  - 0 (Blood Glucose)
RN  - 0 (Brain-Derived Neurotrophic Factor)
RN  - 33X04XA5AT (Lactic Acid)
RN  - 7171WSG8A2 (BDNF protein, human)
SB  - IM
MH  - Blood Glucose/metabolism
MH  - Brain-Derived Neurotrophic Factor/*blood
MH  - Cognition/*physiology
MH  - *Electric Stimulation
MH  - Exercise/*physiology
MH  - Humans
MH  - Lactic Acid/blood
MH  - Oxygen Consumption/physiology
MH  - Young Adult
COIS- Disclosure The authors report no conflicts of interest in this work.
EDAT- 2017/11/11 06:00
MHDA- 2018/04/05 06:00
CRDT- 2017/11/11 06:00
PHST- 2017/11/11 06:00 [pubmed]
PHST- 2018/04/05 06:00 [medline]
PHST- 2017/11/11 06:00 [entrez]
AID - 10.1055/s-0043-120343 [doi]
PST - ppublish
SO  - Int J Sports Med. 2018 Jan;39(1):5-11. doi: 10.1055/s-0043-120343. Epub 2017 Nov 
      10.