PMID- 29127870
OWN - NLM
STAT- MEDLINE
DCOM- 20180823
LR  - 20180823
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 618
DP  - 2018 Mar 15
TI  - Concentrations of several phthalates contaminants in Egyptian bottled water: 
      Effects of storage conditions and estimate of human exposure.
PG  - 142-150
LID - S0048-9697(17)33056-5 [pii]
LID - 10.1016/j.scitotenv.2017.10.337 [doi]
AB  - The occurrence and concentrations of six common phthalates were investigated for 
      the first time in bottled water locally produced in the Egyptian market. The 
      compounds investigated were dimethyl phthalate (DMP), diethyl phthalate (DEP), 
      dibutyl phthalate (DBP), n-butyl benzyl phthalate (BBP), diethyl hexyl phthalate 
      (DEHP), and Di-n-octyl phthalate (D-n-OP). A set of 108 bottled water samples 
      from six different commercial brands of water bottled in transparent polyethylene 
      terephthalate (PET) plastic bottles with high density polyethylene (HDPE) plastic 
      caps were investigated. Water samples were analyzed immediately after purchasing 
      (~2weeks after production), after being stored at room temperature (25+/-5 degrees C), in a 
      refrigerator (4+/-1 degrees C) and outdoor under sun exposure (daylight temperature of 
      40+/-5 degrees C). Samples were stored up to six months depending on the tested condition. 
      Among the target compounds, only DEHP and DBP were detected in the samples 
      analyzed immediately after purchasing with a detection frequency of 50 and 58% 
      and mean concentrations of 0.104 and 0.082mugl(-1) respectively. Significant 
      positive correlation was obtained between the storage time, temperature and the 
      concentration of phthalate compounds detected in the bottled water, indicating 
      possible migration from the PET plastic material as the source. The estimated 
      contribution of bottled water consumption to the tolerable daily intake (TDI) 
      levels of the two most abundant phthalates observed here for adults and toddlers 
      did not exceed 0.16 and 0.72% for DBP while these values were 0.04 and 0.16% for 
      DEHP respectively. These estimated daily intake values from PET bottled water 
      consumption were far below their respective TDI values and therefore should 
      constitute no adverse health effects.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Zaki, Ghada
AU  - Zaki G
AD  - Department of Chemistry, The American University in Cairo, New Cairo 11835, 
      Egypt.
FAU - Shoeib, Tamer
AU  - Shoeib T
AD  - Department of Chemistry, The American University in Cairo, New Cairo 11835, 
      Egypt. Electronic address: T.Shoeib@aucegypt.edu.
LA  - eng
PT  - Journal Article
DEP - 20171108
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Drinking Water)
RN  - 0 (Phthalic Acids)
RN  - 2286E5R2KE (Dibutyl Phthalate)
SB  - IM
MH  - Dibutyl Phthalate
MH  - Dietary Exposure/*analysis
MH  - Drinking Water/*analysis
MH  - Egypt
MH  - *Food Storage
MH  - Gas Chromatography-Mass Spectrometry
MH  - Humans
MH  - Phthalic Acids/*analysis
MH  - Temperature
OTO - NOTNLM
OT  - Bottled water
OT  - Estimated human exposure
OT  - Migration
OT  - Phthalates
OT  - Storage conditions
EDAT- 2017/11/12 06:00
MHDA- 2018/08/24 06:00
CRDT- 2017/11/12 06:00
PHST- 2017/07/22 00:00 [received]
PHST- 2017/10/30 00:00 [revised]
PHST- 2017/10/31 00:00 [accepted]
PHST- 2017/11/12 06:00 [pubmed]
PHST- 2018/08/24 06:00 [medline]
PHST- 2017/11/12 06:00 [entrez]
AID - S0048-9697(17)33056-5 [pii]
AID - 10.1016/j.scitotenv.2017.10.337 [doi]
PST - ppublish
SO  - Sci Total Environ. 2018 Mar 15;618:142-150. doi: 10.1016/j.scitotenv.2017.10.337. 
      Epub 2017 Nov 8.