PMID- 29132668 OWN - NLM STAT- MEDLINE DCOM- 20180618 LR - 20190201 IS - 1557-8607 (Electronic) IS - 0889-8561 (Print) IS - 0889-8561 (Linking) VI - 38 IP - 1 DP - 2018 Feb TI - Diagnosis and Management of Eosinophilic Esophagitis. PG - 125-139 LID - S0889-8561(17)30105-4 [pii] LID - 10.1016/j.iac.2017.09.010 [doi] AB - Unlike traditional food allergies, immunoglobulin E (IgE) is not a key mediator of eosinophilic esophagitis (EoE). Nonetheless, foods antigens are important triggers of EoE, and allergists play an important role in management of this chronic disease. This review addresses insights into the diagnosis and management as it relates to our evolving understanding about the pathogenesis of EoE. CI - Copyright (c) 2017 Elsevier Inc. All rights reserved. FAU - Wilson, Jeffrey M AU - Wilson JM AD - Division of Allergy and Immunology, Department of Medicine, University of Virginia, PO Box 801355, Charlottesville, VA 22908, USA. FAU - McGowan, Emily C AU - McGowan EC AD - Division of Allergy and Immunology, Department of Medicine, University of Virginia, PO Box 801355, Charlottesville, VA 22908, USA; Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, 501 Hopkins Bayview Circle, Baltimore, MD 21224, USA. Electronic address: ekc5v@virginia.edu. LA - eng GR - K23 AI123596/AI/NIAID NIH HHS/United States PT - Journal Article PT - Review DEP - 20171106 PL - United States TA - Immunol Allergy Clin North Am JT - Immunology and allergy clinics of North America JID - 8805635 RN - 0 (Allergens) RN - 0 (Immunoglobulin G) RN - 0 (Steroids) SB - IM MH - Allergens/immunology MH - Animals MH - Chronic Disease MH - *Diet MH - Eosinophilic Esophagitis/*diagnosis/therapy MH - *Food MH - Food Hypersensitivity/*immunology MH - Humans MH - Immunoglobulin G/*metabolism MH - Steroids/therapeutic use PMC - PMC5777515 MID - NIHMS915896 OTO - NOTNLM OT - Elimination diet OT - Eosinophilic esophagitis OT - Food allergy OT - IgG4 OT - Swallowed steroids EDAT- 2017/11/15 06:00 MHDA- 2018/06/19 06:00 PMCR- 2019/02/01 CRDT- 2017/11/15 06:00 PHST- 2017/11/15 06:00 [entrez] PHST- 2017/11/15 06:00 [pubmed] PHST- 2018/06/19 06:00 [medline] PHST- 2019/02/01 00:00 [pmc-release] AID - S0889-8561(17)30105-4 [pii] AID - 10.1016/j.iac.2017.09.010 [doi] PST - ppublish SO - Immunol Allergy Clin North Am. 2018 Feb;38(1):125-139. doi: 10.1016/j.iac.2017.09.010. Epub 2017 Nov 6.