PMID- 29134799 OWN - NLM STAT- MEDLINE DCOM- 20180611 LR - 20181202 IS - 1520-5851 (Electronic) IS - 0013-936X (Linking) VI - 51 IP - 23 DP - 2017 Dec 5 TI - E-Waste Driven Pollution in Pakistan: The First Evidence of Environmental and Human Exposure to Flame Retardants (FRs) in Karachi City. PG - 13895-13905 LID - 10.1021/acs.est.7b03159 [doi] AB - Informal e-waste recycling activities have been shown to be a major emitter of organic flame retardants (FRs), contributing to both environmental and human exposure to laborers at e-waste recycling sites in some West African countries, as well as in China and India. The main objective of this study was to determine the levels of selected organic FRs in both air and soil samples collected from areas with intensive informal e-waste recycling activities in Karachi, Pakistan. Dechlorane Plus (DP) and "novel" brominated flame retardants (NBFRs) were often detected in high concentrations in soils, while phosphorus-based FRs (OPFRs) dominated atmospheric samples. Among individual substances and substance groups, decabromodiphenyl ether (BDE-209) (726 ng/g), decabromodiphenyl ethane (DBDPE) (551 ng/g), 1,2-bis(2,4,6-tribromophenoxy) ethane (BTBPE) (362 ng/g), and triphenyl-phosphate ( summation operatorTPP) (296 ng/g) were found to be prevalent in soils, while OPFR congeners (5903-24986 ng/m(3)) were prevalent in air. The two major e-waste recycling areas (Shershah and Lyari) were highly contaminated with FRs, suggesting informal e-waste recycling activities as a major emission source of FRs in the environment in Karachi City. However, the hazards associated with exposure to PM(2.5) appear to exceed those attributed to exposure to selected FRs via inhalation and soil ingestion. FAU - Iqbal, Mehreen AU - Iqbal M AUID- ORCID: 0000-0002-0520-4972 AD - Environmental Biology and Ecotoxicology Laboratory, Department of Environmental Sciences, Faculty of Biological Sciences, Quaid-I-Azam University , Islamabad 45320, Pakistan. FAU - Syed, Jabir Hussain AU - Syed JH AUID- ORCID: 0000-0003-0942-8495 AD - State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences , Guangzhou 510640, China. AD - Department of Meteorology, COMSATS Institute of Information Technology (CIIT) , Park Road, Tarlai Kalan, Islamabad 45550, Pakistan. FAU - Breivik, Knut AU - Breivik K AD - Norwegian Institute for Air Research , Box 100, NO-2027 Kjeller, Norway. AD - University of Oslo , Department of Chemistry, Box 1033, NO-0315 Oslo, Norway. FAU - Chaudhry, Muhammad Jamshed Iqbal AU - Chaudhry MJI AD - WWF-Pakistan , Ferozpur Road, PO Box 5180, Lahore 54600, Pakistan. FAU - Li, Jun AU - Li J AUID- ORCID: 0000-0002-3637-1642 AD - State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences , Guangzhou 510640, China. FAU - Zhang, Gan AU - Zhang G AD - State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences , Guangzhou 510640, China. FAU - Malik, Riffat Naseem AU - Malik RN AD - Environmental Biology and Ecotoxicology Laboratory, Department of Environmental Sciences, Faculty of Biological Sciences, Quaid-I-Azam University , Islamabad 45320, Pakistan. LA - eng PT - Journal Article DEP - 20171121 PL - United States TA - Environ Sci Technol JT - Environmental science & technology JID - 0213155 RN - 0 (Flame Retardants) RN - 0 (Halogenated Diphenyl Ethers) SB - IM MH - Africa, Western MH - China MH - *Electronic Waste MH - *Environmental Monitoring MH - *Flame Retardants MH - Halogenated Diphenyl Ethers MH - Humans MH - India MH - Pakistan EDAT- 2017/11/15 06:00 MHDA- 2018/06/12 06:00 CRDT- 2017/11/15 06:00 PHST- 2017/11/15 06:00 [pubmed] PHST- 2018/06/12 06:00 [medline] PHST- 2017/11/15 06:00 [entrez] AID - 10.1021/acs.est.7b03159 [doi] PST - ppublish SO - Environ Sci Technol. 2017 Dec 5;51(23):13895-13905. doi: 10.1021/acs.est.7b03159. Epub 2017 Nov 21.