PMID- 29138680 OWN - NLM STAT- MEDLINE DCOM- 20180719 LR - 20221207 IS - 1942-0994 (Electronic) IS - 1942-0900 (Print) IS - 1942-0994 (Linking) VI - 2017 DP - 2017 TI - Enhancement of Antioxidant Mechanisms and Reduction of Oxidative Stress in Chickens after the Administration of Drinking Water Enriched with Polyphenolic Powder from Olive Mill Waste Waters. PG - 8273160 LID - 10.1155/2017/8273160 [doi] LID - 8273160 AB - The aim of the study was to examine the effects of a polyphenolic powder from olive mill wastewater (OMWW) administered through drinking water, on chickens' redox status. Thus, 75 chickens were divided into three groups. Group A was given just drinking water, while groups B and C were given drinking water containing 20 and 50 mug/ml of polyphenols, respectively, for 45 days. The antioxidant effects of the polyphenolic powder were assessed by measuring oxidative stress biomarkers in blood after 25 and 45 days of treatment. These markers were total antioxidant capacity (TAC), protein carbonyls (CARB), thiobarbituric acid reactive species (TBARS) and superoxide dismutase activity (SOD) in plasma, and glutathione (GSH) and catalase activity in erythrocytes. The results showed that CARB and TBARS were decreased significantly in groups B and C, and SOD decreased in group B compared to that in group A. TAC was increased significantly in group C and GSH was increased in group B, while catalase activity was increased in groups B and C compared to that in group A. In conclusion, this is the first study showing that supplementation of chickens with polyphenols from OMWW through drinking water enhanced their antioxidant mechanisms and reduced oxidative stress-induced damage. FAU - Papadopoulou, Aliki AU - Papadopoulou A AD - Department of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. FAU - Petrotos, Konstantinos AU - Petrotos K AD - Department of Biosystems Engineering, Technical Education Institute of Thessaly, 41110 Larissa, Greece. FAU - Stagos, Dimitrios AU - Stagos D AUID- ORCID: 0000-0002-7133-2008 AD - Department of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. FAU - Gerasopoulos, Konstantinos AU - Gerasopoulos K AD - Department of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. FAU - Maimaris, Antonios AU - Maimaris A AD - Department of Animal Production, Technical Education Institute of Thessaly, 41110 Larissa, Greece. FAU - Makris, Haralampos AU - Makris H AD - Department of Animal Production, Technical Education Institute of Thessaly, 41110 Larissa, Greece. FAU - Kafantaris, Ioannis AU - Kafantaris I AUID- ORCID: 0000-0002-8371-7263 AD - Department of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. FAU - Makri, Sotiria AU - Makri S AD - Department of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. FAU - Kerasioti, Efthalia AU - Kerasioti E AD - Department of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. FAU - Halabalaki, Maria AU - Halabalaki M AD - Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece. FAU - Brieudes, Vincent AU - Brieudes V AD - Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece. FAU - Ntasi, Georgia AU - Ntasi G AD - PharmaGnose S.A., Papathanasiou 24, 34100 Eyboia, Greece. FAU - Kokkas, Stylianos AU - Kokkas S AD - Department of Biosystems Engineering, Technical Education Institute of Thessaly, 41110 Larissa, Greece. FAU - Tzimas, Pavlos AU - Tzimas P AD - Department of Agricultural Engineering Technologists, Technical Education Institute of Thessaly, 41110 Larissa, Greece. FAU - Goulas, Panagiotis AU - Goulas P AD - Department of Animal Production, Technical Education Institute of Thessaly, 41110 Larissa, Greece. FAU - Zakharenko, Alexander M AU - Zakharenko AM AUID- ORCID: 0000-0002-9520-8271 AD - Scientific Educational Centre of Nanotechnology, Far Eastern Federal University, Engineering School, 10 Pushkinskaya Street, 690950 Vladivostok, Russia. FAU - Golokhvast, Kirill S AU - Golokhvast KS AUID- ORCID: 0000-0002-4873-2281 AD - Scientific Educational Centre of Nanotechnology, Far Eastern Federal University, Engineering School, 10 Pushkinskaya Street, 690950 Vladivostok, Russia. FAU - Tsatsakis, Aristidis AU - Tsatsakis A AD - Laboratory of Toxicology, School of Medicine, University of Crete, 71003 Heraklion, Greece. FAU - Kouretas, Demetrios AU - Kouretas D AUID- ORCID: 0000-0002-7469-6640 AD - Department of Biochemistry and Biotechnology, University of Thessaly, Viopolis, 41500 Larissa, Greece. LA - eng PT - Journal Article DEP - 20170824 PL - United States TA - Oxid Med Cell Longev JT - Oxidative medicine and cellular longevity JID - 101479826 RN - 0 (Antioxidants) RN - 0 (Drinking Water) RN - 0 (Polyphenols) RN - 0 (Waste Water) SB - IM MH - Animals MH - Antioxidants/*metabolism MH - Chickens MH - Drinking Water/*chemistry MH - Male MH - Oxidative Stress/*drug effects MH - Polyphenols/pharmacology/*therapeutic use MH - Wastewater/*chemistry PMC - PMC5613686 EDAT- 2017/11/16 06:00 MHDA- 2018/07/20 06:00 PMCR- 2017/08/24 CRDT- 2017/11/16 06:00 PHST- 2017/05/14 00:00 [received] PHST- 2017/07/21 00:00 [revised] PHST- 2017/07/26 00:00 [accepted] PHST- 2017/11/16 06:00 [entrez] PHST- 2017/11/16 06:00 [pubmed] PHST- 2018/07/20 06:00 [medline] PHST- 2017/08/24 00:00 [pmc-release] AID - 10.1155/2017/8273160 [doi] PST - ppublish SO - Oxid Med Cell Longev. 2017;2017:8273160. doi: 10.1155/2017/8273160. Epub 2017 Aug 24.