PMID- 29156865
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 1303-6165 (Electronic)
IS  - 1300-0144 (Linking)
VI  - 47
IP  - 4
DP  - 2017 Aug 23
TI  - Antibacterial resistance patterns and incidence of hospital-acquired 
      Staphylococcus aureus bacteremia in a tertiary care educational hospital in 
      Turkey: a perspective from 2001 to 2013.
PG  - 1210-1215
LID - 10.3906/sag-1607-63 [doi]
AB  - Background/aim: Staphylococcus aureus is an important nosocomial pathogen and a 
      successful antimicrobial-resistance developer. In this study we retrospectively 
      evaluated the resistance patterns and incidence of microbiologically confirmed 
      nosocomial bacteremia (MCNB) related S. aureus strains between 2001 and 2013. 
      Materials and methods: Any patient in whom S. aureus was isolated in at least one 
      set of blood cultures (sent to the bacteriology laboratory 72 h after hospital 
      admission) was considered to have MCNB. Results: The methicillin-resistant S. 
      aureus (MRSA) rate in 2001 was 73.8% whereas it was 36.2% in 2013. When the 
      2001-2003 and 2011?2013 periods were compared, resistance to oxacillin, 
      levofloxacin, gentamicin, erythromycin, and clindamycin decreased significantly 
      (P < 0.05). When we evaluated the total S. aureus, MRSA, and 
      methicillin-sensitive S. aureus (MSSA) bacteremia rates per 1000 days and 1000 
      patients, there was an increase in the 2004?2005 period, which was followed by a 
      slight decrease until 2013 (P < 0.05). There was a plateau in MCNB-related S. 
      aureus rates between 2008 and 2011. Conclusion: There was a decrease in overall 
      S. aureus and MRSA bacteremia incidence as well as MRSA rates except for a 
      plateau between 2008 and 2011. This steady decrease in the resistance rates is 
      most probably due to the 2003 budget application and application of antimicrobial 
      stewardship.
FAU - Sipahi, Oguz Resat
AU  - Sipahi OR
FAU - Uysal, Serhat
AU  - Uysal S
FAU - Aydemir, Sabire Sohret
AU  - Aydemir SS
FAU - Pullukcu, Husnu
AU  - Pullukcu H
FAU - Tasbakan, Meltem
AU  - Tasbakan M
FAU - Tunger, Alper
AU  - Tunger A
FAU - Cilli, Fatma Feriha
AU  - Cilli FF
FAU - Yamazhan, Tansu
AU  - Yamazhan T
FAU - Arda, Bilgin
AU  - Arda B
FAU - Sipahi, Hilal
AU  - Sipahi H
FAU - Ulusoy, Sercan
AU  - Ulusoy S
LA  - eng
PT  - Journal Article
DEP - 20170823
PL  - Turkey
TA  - Turk J Med Sci
JT  - Turkish journal of medical sciences
JID - 9441758
OTO - NOTNLM
OT  - Antimicrobial resistance epidemiology
OT  - bacteremia
OT  - Staphylococcus aureus
OT  - MRSA
OT  - infectious diseases
OT  - erythromycin
OT  - glycopeptides
OT  - vancomycin
OT  - teicoplanin
OT  - incidence
EDAT- 2017/11/22 06:00
MHDA- 2017/11/22 06:01
CRDT- 2017/11/22 06:00
PHST- 2017/11/22 06:00 [pubmed]
PHST- 2017/11/22 06:01 [medline]
PHST- 2017/11/22 06:00 [entrez]
AID - 10.3906/sag-1607-63 [doi]
PST - epublish
SO  - Turk J Med Sci. 2017 Aug 23;47(4):1210-1215. doi: 10.3906/sag-1607-63.