PMID- 29159909
OWN - NLM
STAT- MEDLINE
DCOM- 20180918
LR  - 20180918
IS  - 1439-0272 (Electronic)
IS  - 0303-4569 (Linking)
VI  - 50
IP  - 3
DP  - 2018 Apr
TI  - Essential role of brain-derived neurotrophic factor (bdnf) in diabetic erectile 
      dysfunction.
LID - 10.1111/and.12924 [doi]
AB  - Erectile dysfunction (ED) is a worldwide problem threatens men's health. The 
      incidence of ED in diabetic patients is higher than that in the healthy 
      population. The incidence of peripheral and autonomic neuropathy is significantly 
      higher in diabetic patients than in normal men. Vasomotor nerves play an 
      important role in the regulation of erectile function. Degeneration of autonomic 
      and sensory nerves is a common type of diabetic neuropathy (DNP) and is closely 
      related to erectile function. Brain-derived neurotrophic factor (BDNF) has been 
      demonstrated to improve diabetic erectile dysfunction in rat models and in 
      humans. However, this process has not yet been fully elucidated yet. In this 
      article, we summarise the mechanisms by which BDNF improves diabetic erectile 
      dysfunction.
CI  - (c) 2017 Blackwell Verlag GmbH.
FAU - Hu, L
AU  - Hu L
AUID- ORCID: 0000-0002-1423-4620
AD  - Department of Urology, Shandong Provincial Hospital Affiliated to Shandong 
      University, Jinan, China.
AD  - Department of Urology, Shandong Zaozhuang Municipal Hospital, Zaozhuang, China.
FAU - Qi, S
AU  - Qi S
AD  - Department of Neurology, Shandong Zaozhuang Municipal Hospital, Zaozhuang, China.
FAU - Zhang, K
AU  - Zhang K
AD  - Department of Urology, Shandong Provincial Hospital Affiliated to Shandong 
      University, Jinan, China.
FAU - Fu, Q
AU  - Fu Q
AD  - Department of Urology, Shandong Provincial Hospital Affiliated to Shandong 
      University, Jinan, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20171121
PL  - Germany
TA  - Andrologia
JT  - Andrologia
JID - 0423506
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Animals
MH  - Brain-Derived Neurotrophic Factor/*metabolism
MH  - Diabetic Neuropathies/*metabolism
MH  - Erectile Dysfunction/*metabolism
MH  - Humans
MH  - Male
MH  - Penile Erection/physiology
OTO - NOTNLM
OT  - Brain-derived neurotrophic factor (BDNF)
OT  - diabetic neuropathy
OT  - erectile dysfunction
EDAT- 2017/11/22 06:00
MHDA- 2018/09/19 06:00
CRDT- 2017/11/22 06:00
PHST- 2017/09/14 00:00 [accepted]
PHST- 2017/11/22 06:00 [pubmed]
PHST- 2018/09/19 06:00 [medline]
PHST- 2017/11/22 06:00 [entrez]
AID - 10.1111/and.12924 [doi]
PST - ppublish
SO  - Andrologia. 2018 Apr;50(3). doi: 10.1111/and.12924. Epub 2017 Nov 21.