PMID- 29161574
OWN - NLM
STAT- MEDLINE
DCOM- 20180530
LR  - 20181202
IS  - 1873-2976 (Electronic)
IS  - 0960-8524 (Linking)
VI  - 250
DP  - 2018 Feb
TI  - Fast spectroscopic monitoring of inhibitors in the 2G ethanol process.
PG  - 148-154
LID - S0960-8524(17)32007-2 [pii]
LID - 10.1016/j.biortech.2017.11.033 [doi]
AB  - One of the main challenges of second generation (2G) ethanol production is the 
      high quantities of phenolic compounds and furan derivatives generated in the 
      pretreatment of the lignocellulosic biomass, which inhibit the enzymatic 
      hydrolysis and fermentation steps. Fast monitoring of these inhibitory compounds 
      could provide better control of the pretreatment, hydrolysis, and fermentation 
      processes by enabling the implementation of strategic process control actions. We 
      investigated the feasibility of monitoring these inhibitory compounds by 
      ultraviolet-visible (UV-Vis) spectroscopy associated with partial least squares 
      (PLS) regression. Hydroxymethylfurfural, furfural, vanillin, and ferulic and 
      p-coumaric acids generated during different severities of liquid hot water 
      pretreatment of sugarcane bagasse were quantified with highly accuracy. In 
      cross-validation (leave-one-out), the PLS-UV-Vis method presented root mean 
      square error of prediction (RMSECV) of around only 5.0%. The results demonstrated 
      that the monitoring performance achieved with PLS-UV-Vis could support future 
      studies of optimization and control protocols for application in industrial 
      processes.
CI  - Copyright (c) 2017 Elsevier Ltd. All rights reserved.
FAU - Pinto, Ariane S S
AU  - Pinto ASS
AD  - Graduate Program of Chemical Engineering, Federal University of Sao Carlos, 
      13565-905, PO Box 676, Sao Carlos, SP, Brazil; Embrapa Instrumentation, Rua XV de 
      Novembro 1452, 13560-970 Sao Carlos, SP, Brazil.
FAU - Ribeiro, Marcelo P A
AU  - Ribeiro MPA
AD  - Graduate Program of Chemical Engineering, Federal University of Sao Carlos, 
      13565-905, PO Box 676, Sao Carlos, SP, Brazil; Chemical Engineering Department, 
      Federal University of Sao Carlos, 13565-905, PO Box 676, Sao Carlos, SP, Brazil.
FAU - Farinas, Cristiane S
AU  - Farinas CS
AD  - Graduate Program of Chemical Engineering, Federal University of Sao Carlos, 
      13565-905, PO Box 676, Sao Carlos, SP, Brazil; Embrapa Instrumentation, Rua XV de 
      Novembro 1452, 13560-970 Sao Carlos, SP, Brazil. Electronic address: 
      cristiane.farinas@embrapa.br.
LA  - eng
PT  - Journal Article
DEP - 20171114
PL  - England
TA  - Bioresour Technol
JT  - Bioresource technology
JID - 9889523
RN  - 3K9958V90M (Ethanol)
SB  - IM
MH  - Biomass
MH  - *Ethanol
MH  - *Fermentation
MH  - Hydrolysis
MH  - Least-Squares Analysis
MH  - Saccharum
OTO - NOTNLM
OT  - Furaldehydes
OT  - Liquid hot water pretreatment
OT  - Partial least squares (PLS) regression
OT  - Phenolic compounds
OT  - Sugarcane bagasse
OT  - Ultraviolet-visible (UV-Vis) spectroscopy
EDAT- 2017/11/22 06:00
MHDA- 2018/05/31 06:00
CRDT- 2017/11/22 06:00
PHST- 2017/09/15 00:00 [received]
PHST- 2017/11/09 00:00 [revised]
PHST- 2017/11/10 00:00 [accepted]
PHST- 2017/11/22 06:00 [pubmed]
PHST- 2018/05/31 06:00 [medline]
PHST- 2017/11/22 06:00 [entrez]
AID - S0960-8524(17)32007-2 [pii]
AID - 10.1016/j.biortech.2017.11.033 [doi]
PST - ppublish
SO  - Bioresour Technol. 2018 Feb;250:148-154. doi: 10.1016/j.biortech.2017.11.033. 
      Epub 2017 Nov 14.