PMID- 29163841
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 1949-2553 (Electronic)
IS  - 1949-2553 (Linking)
VI  - 8
IP  - 52
DP  - 2017 Oct 27
TI  - Assessing right ventricular function in pulmonary hypertension patients and the 
      correlation with the New York Heart Association (NYHA) classification.
PG  - 90421-90429
LID - 10.18632/oncotarget.19026 [doi]
AB  - This investigation aimed to compare the pressure-volume loop (PV loop) 
      measurements in three less symptomatic categories (New York Heart Association 
      classes , NYHA I, II, and III) of pulmonary hypertension (PH) patients since NYHA 
      classification system performance is limited by the shortcomings discussed above. 
      Thirty-six patients were enrolled in this study with PV loop measurement 
      acquisition via micro-conductance catheters. Functional classification according 
      to NYHA was determined with comprehensive assessing function and activity. 
      Catheterization and MRI was applied to obtain variables on right ventricle (RV) 
      functions. Correlation test was applied to test the relationship between measured 
      PV loop measurements and NYHA classification. A group of PV loop measurements, 
      including end-systolic pressure (RVESP) RV end-diastolic pressure (RVEDP), and RV 
      arterial elastance (RVEa), are well correlated with three NYHA classes (I, II, 
      and III). Moreover, RVESP and RVEa significantly correlated with two groups of 
      NYHA classes (I and II/III) while RVEDP, RV end-diastolic volume (RVEDV), and RV 
      end-systolic volume (RVESV) significantly moderately correlated with two groups 
      of NYHA classes (I/II and III). This study suggests the promising role of PV loop 
      analysis in assessing functional capacity in progressive but less symptomatic PH 
      patients.
FAU - Shang, Xiaoke
AU  - Shang X
AD  - Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, 
      Huazhong University of Science and Technology, Hubei Province 430222, China.
FAU - Xiao, Shuna
AU  - Xiao S
AD  - Department of Pediatric Intensive Care Unit, Hubei Maternal and Child Health 
      Hospital, Hubei Province 430070, China.
FAU - Dong, Nianguo
AU  - Dong N
AD  - Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, 
      Huazhong University of Science and Technology, Hubei Province 430222, China.
FAU - Lu, Rong
AU  - Lu R
AD  - Department of Intensive Care Unit, Wuhan No.1 Hospital, Tongji Medical College, 
      Huazhong University of Science and Technology, Hubei Province 430222, China.
FAU - Wang, Lijun
AU  - Wang L
AD  - Department of Intervention, Wuhan Asia Heart Hospital, Hubei Province 430022, 
      China.
FAU - Wang, Bin
AU  - Wang B
AD  - Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, 
      Huazhong University of Science and Technology, Hubei Province 430222, China.
FAU - Chen, Yousan
AU  - Chen Y
AD  - Department of Radiology, Wuhan General Hospital of CPLA, Guangzhou Military 
      Command, Hubei Province 430070, China.
FAU - Zhong, Liang
AU  - Zhong L
AD  - National Heart Centre Singapore, 169609, Singapore.
AD  - Duke NUS Medical School, 169857, Singapore.
FAU - Liu, Mei
AU  - Liu M
AD  - Department of Intensive Care Unit, Wuhan No.1 Hospital, Tongji Medical College, 
      Huazhong University of Science and Technology, Hubei Province 430222, China.
LA  - eng
PT  - Journal Article
DEP - 20170705
PL  - United States
TA  - Oncotarget
JT  - Oncotarget
JID - 101532965
PMC - PMC5685762
OTO - NOTNLM
OT  - New York Heart Association (NYHA)
OT  - PV Loop
OT  - pulmonary hypertension (PH)
OT  - right ventricular
COIS- CONFLICTS OF INTEREST None.
EDAT- 2017/11/23 06:00
MHDA- 2017/11/23 06:01
PMCR- 2017/10/27
CRDT- 2017/11/23 06:00
PHST- 2017/02/23 00:00 [received]
PHST- 2017/06/17 00:00 [accepted]
PHST- 2017/11/23 06:00 [entrez]
PHST- 2017/11/23 06:00 [pubmed]
PHST- 2017/11/23 06:01 [medline]
PHST- 2017/10/27 00:00 [pmc-release]
AID - 19026 [pii]
AID - 10.18632/oncotarget.19026 [doi]
PST - epublish
SO  - Oncotarget. 2017 Jul 5;8(52):90421-90429. doi: 10.18632/oncotarget.19026. 
      eCollection 2017 Oct 27.