PMID- 29166676
OWN - NLM
STAT- MEDLINE
DCOM- 20190418
LR  - 20190418
IS  - 1098-8785 (Electronic)
IS  - 0735-1631 (Linking)
VI  - 35
IP  - 5
DP  - 2018 Apr
TI  - Comparison of Melatonin Levels in the Colostrum between Vaginal Delivery and 
      Cesarean Delivery.
PG  - 481-485
LID - 10.1055/s-0037-1608681 [doi]
AB  - OBJECTIVE:  This study aims to compare melatonin levels in colostrum between 
      vaginal and cesarean delivery. STUDY DESIGN:  This cross-sectional study was 
      conducted with 139 mothers who gave live births between February 2016 and 
      December 2016. The mothers were divided into three groups according to the mode 
      of delivery: 60 mothers (43.2%) in the vaginal delivery group, 47 mothers (33.8%) 
      in the elective cesarean delivery, and 32 mothers (23.0%) in the emergency 
      cesarean delivery group. Colostrum of the mothers was taken between 01:00 and 
      03:00 a.m. within 48 to 72 hours following the delivery, and the melatonin levels 
      were measured using the enzyme-linked immunosorbent assay (ELISA) and compared 
      between the groups. RESULTS:  The melatonin levels in the colostrum were the 
      highest in the vaginal delivery group, lower in the elective cesarean section 
      group, and the lowest in the emergency cesarean group (265.7 +/- 74.3, 
      204.9 +/- 55.6, and 167.1 +/- 48.1, respectively; p < 0.001). The melatonin levels in 
      the colostrum did not differ according to the demographic characteristics of the 
      mothers, gestational age, birth weight, newborn sex, the Appearance, Pulse, 
      Grimace, Activity, and Respiration (APGAR) scores, and for the requirement for 
      neonatal intensive care. CONCLUSION:  Our study results showed that melatonin 
      levels in the colostrum of the mothers who delivered vaginally were higher than 
      those who delivered by cesarean section. Considering the known benefits of 
      melatonin for the newborns, we believe that vaginal delivery poses an advantage.
CI  - Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
FAU - Namli Kalem, Muberra
AU  - Namli Kalem M
AD  - Department of Obstetrics and Gynecology, Liv Hospital, Ankara, Turkey.
FAU - Kalem, Ziya
AU  - Kalem Z
AD  - Gurgan Clinic Women's Health, Infertility and IVF Center, Ankara, Turkey.
FAU - Yuce, Tuncay
AU  - Yuce T
AD  - Department of Obstetrics and Gynecology, Ankara University School of Medicine, 
      Ankara, Turkey.
FAU - Bakirarar, Batuhan
AU  - Bakirarar B
AD  - Department of Biostatistics, Ankara University School of Medicine, Ankara, 
      Turkey.
FAU - Soylemez, Feride
AU  - Soylemez F
AD  - Department of Obstetrics and Gynecology, Ankara University School of Medicine, 
      Ankara, Turkey.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20171122
PL  - United States
TA  - Am J Perinatol
JT  - American journal of perinatology
JID - 8405212
RN  - JL5DK93RCL (Melatonin)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Cesarean Section
MH  - Colostrum/*chemistry
MH  - Cross-Sectional Studies
MH  - Delivery, Obstetric/*methods
MH  - Female
MH  - Gestational Age
MH  - Humans
MH  - Melatonin/*analysis
MH  - Pregnancy
MH  - Turkey
MH  - Young Adult
COIS- None.
EDAT- 2017/11/23 06:00
MHDA- 2019/04/19 06:00
CRDT- 2017/11/23 06:00
PHST- 2017/11/23 06:00 [pubmed]
PHST- 2019/04/19 06:00 [medline]
PHST- 2017/11/23 06:00 [entrez]
AID - 10.1055/s-0037-1608681 [doi]
PST - ppublish
SO  - Am J Perinatol. 2018 Apr;35(5):481-485. doi: 10.1055/s-0037-1608681. Epub 2017 
      Nov 22.