PMID- 29171203
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200929
IS  - 1738-5520 (Print)
IS  - 1738-5555 (Electronic)
IS  - 1738-5520 (Linking)
VI  - 48
IP  - 1
DP  - 2018 Jan
TI  - Association of Syntax Score II with Contrast-induced Nephropathy and Hemodialysis 
      Requirement in Patients with ST Segment Elevation Myocardial Infarction 
      Undergoing Primary Percutaneous Coronary Intervention.
PG  - 59-70
LID - 10.4070/kcj.2017.0058 [doi]
AB  - BACKGROUND AND OBJECTIVES: Contrast-induced nephropathy (CIN) is a common 
      complication of primary percutaneous coronary intervention (pPCI) and is 
      associated with high mortality and morbidity and long hospital stay in patients 
      with ST elevation myocardial infarction (STEMI). The Syntax Score (SS) has 
      previously been studied in STEMI patients, and it was associated with increased 
      CIN development and long-term mortality. This study investigates a possible 
      relationship between CIN development and Syntax Score II (SSII) and compares SS 
      and SSII by assessing CIN risk in STEMI patients treated with pPCI. METHODS: A 
      total of 1,234 patients who underwent pPCI were divided into 2 groups according 
      to CIN development. Patients with CIN were further divided into 2 groups 
      according to whether or not they required hemodialysis. Reclassification tables, 
      net reclassification improvement, and integrated discriminative improvement 
      methods were used to assess the additive predictive value of SSII for predicting 
      CIN. RESULTS: In the present study, 166 patients (13.5%) had CIN. Although both 
      SS and SSII were significantly higher in CIN patients, only SSII was an 
      independent predictor of CIN (odds ratio [OR], 1.031; 95% confidence interval 
      [CI], 1.012-1.051; p<0.001) and hemodialysis requirement (OR, 1.078; 95% CI, 
      1.046-1.078; p<0.001). When comparing SSII and SS in their ability to determine 
      CIN risk, we found SSII to have a reclassification improvement of 27.59% 
      (p<0.001) and an integrated discrimination improvement of 9.1% (p<0.001). 
      CONCLUSIONS: The combination of clinical and anatomic variables can more 
      accurately identify patients who are at high risk for CIN after pPCI. While SSII 
      is harder to calculate than SS, it provides better prediction for CIN and 
      hemodialysis requirement than SS.
CI  - Copyright (c) 2018. The Korean Society of Cardiology
FAU - Rencuzogullari, Ibrahim
AU  - Rencuzogullari I
AUID- ORCID: 0000-0002-0070-9197
AD  - Department of Cardiology, Kafkas University Medical Faculty, Kars, Turkey. 
      rencuzog@gmail.com.
FAU - Cagdas, Metin
AU  - Cagdas M
AUID- ORCID: 0000-0001-6704-9886
AD  - Department of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.
FAU - Karakoyun, Suleyman
AU  - Karakoyun S
AUID- ORCID: 0000-0002-7817-7098
AD  - Department of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.
FAU - Karabag, Yavuz
AU  - Karabag Y
AUID- ORCID: 0000-0002-8156-315X
AD  - Department of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.
FAU - Yesin, Mahmut
AU  - Yesin M
AUID- ORCID: 0000-0002-2515-1265
AD  - Department of Cardiology, Kars Harakani State Hospital, Kars, Turkey.
FAU - Gursoy, Mustafa Ozan
AU  - Gursoy MO
AUID- ORCID: 0000-0003-3623-7029
AD  - Department of Cardiology, Gaziemir State Hospital, Izmir, Turkey.
FAU - Artac, Inanc
AU  - Artac I
AD  - Department of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.
FAU - Ilis, Dogan
AU  - Ilis D
AD  - Department of Cardiology, Kafkas University Medical Faculty, Kars, Turkey.
FAU - Efe, Suleyman Cagan
AU  - Efe SC
AUID- ORCID: 0000-0002-6067-6841
AD  - Department of Cardiology, Agri State Hospital, Agri, Turkey.
FAU - Tural, Kevser
AU  - Tural K
AUID- ORCID: 0000-0003-4490-037X
AD  - Department of Cardiovascular Surgery, Kafkas University Medical Faculty, Kars, 
      Turkey.
FAU - Tanboga, Ibrahim Halil
AU  - Tanboga IH
AD  - Department of Cardiology, Ataturk University Medical Faculty, Erzurum, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20171115
PL  - Korea (South)
TA  - Korean Circ J
JT  - Korean circulation journal
JID - 101247141
CIN - Korean Circ J. 2018 Jan;48(1):84-85. PMID: 29322699
PMC - PMC5764871
OTO - NOTNLM
OT  - Contrast induced nephropathy.
OT  - ST segment elevation myocardial infarction
OT  - Syntax score II
COIS- The authors have no financial conflicts of interest.
EDAT- 2017/11/25 06:00
MHDA- 2017/11/25 06:01
PMCR- 2018/01/01
CRDT- 2017/11/25 06:00
PHST- 2017/03/17 00:00 [received]
PHST- 2017/06/30 00:00 [revised]
PHST- 2017/09/26 00:00 [accepted]
PHST- 2017/11/25 06:00 [pubmed]
PHST- 2017/11/25 06:01 [medline]
PHST- 2017/11/25 06:00 [entrez]
PHST- 2018/01/01 00:00 [pmc-release]
AID - 48.e8 [pii]
AID - 10.4070/kcj.2017.0058 [doi]
PST - ppublish
SO  - Korean Circ J. 2018 Jan;48(1):59-70. doi: 10.4070/kcj.2017.0058. Epub 2017 Nov 
      15.