PMID- 29172072 OWN - NLM STAT- MEDLINE DCOM- 20180821 LR - 20181202 IS - 1879-6265 (Electronic) IS - 1879-6257 (Linking) VI - 27 DP - 2017 Dec TI - Reproductive effects of arteriviruses: equine arteritis virus and porcine reproductive and respiratory syndrome virus infections. PG - 57-70 LID - S1879-6257(17)30104-9 [pii] LID - 10.1016/j.coviro.2017.11.005 [doi] AB - Equine arteritis virus (EAV) and porcine reproductive and respiratory syndrome virus (PRRSV) are the most economically important members of the family Arteriviridae. EAV and PRRSV cause reproductive and respiratory disease in equids and swine, respectively and constitute a significant economic burden to equine and swine industries around the world. Furthermore, they both cause abortion in pregnant animals and establish persistent infection in their natural hosts, which fosters viral shedding in semen leading to sexual transmission. The primary focus of this article is to provide an update on the effects of these two viruses on the reproductive tract of their natural hosts and provide a comparative analysis of clinical signs, virus-host interactions, mechanisms of viral pathogenesis and viral persistence. CI - Copyright (c) 2017 Elsevier B.V. All rights reserved. FAU - Balasuriya, Udeni Br AU - Balasuriya UB AD - Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, USA. Electronic address: ubalasuriya@uky.edu. FAU - Carossino, Mariano AU - Carossino M AD - Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, USA. LA - eng PT - Comparative Study PT - Journal Article PT - Review DEP - 20171121 PL - Netherlands TA - Curr Opin Virol JT - Current opinion in virology JID - 101560941 SB - IM MH - Animals MH - Arterivirus Infections/transmission/*veterinary/virology MH - Equartevirus/*pathogenicity/physiology MH - Female MH - Horse Diseases/economics/transmission/virology MH - Horses MH - *Host-Pathogen Interactions MH - Male MH - Porcine Reproductive and Respiratory Syndrome/*transmission/virology MH - Porcine respiratory and reproductive syndrome virus/*pathogenicity MH - Pregnancy MH - Pregnancy Complications, Infectious/*veterinary/virology MH - Swine MH - Swine Diseases/economics/transmission/virology EDAT- 2017/11/25 06:00 MHDA- 2018/08/22 06:00 CRDT- 2017/11/25 06:00 PHST- 2017/11/02 00:00 [received] PHST- 2017/11/05 00:00 [accepted] PHST- 2017/11/25 06:00 [pubmed] PHST- 2018/08/22 06:00 [medline] PHST- 2017/11/25 06:00 [entrez] AID - S1879-6257(17)30104-9 [pii] AID - 10.1016/j.coviro.2017.11.005 [doi] PST - ppublish SO - Curr Opin Virol. 2017 Dec;27:57-70. doi: 10.1016/j.coviro.2017.11.005. Epub 2017 Nov 21.