PMID- 29185210
OWN - NLM
STAT- MEDLINE
DCOM- 20190812
LR  - 20211112
IS  - 1724-6059 (Electronic)
IS  - 1121-8428 (Linking)
VI  - 31
IP  - 3
DP  - 2018 Jun
TI  - Acute kidney injury based on the KDIGO criteria among ST elevation myocardial 
      infarction patients treated by primary percutaneous intervention.
PG  - 423-428
LID - 10.1007/s40620-017-0461-3 [doi]
AB  - BACKGROUND: Acute kidney injury (AKI) following acute ST elevation myocardial 
      infarction (STEMI) is associated with adverse outcomes. The recently proposed 
      KDIGO criteria suggested modifications to the consensus classification system for 
      AKI, namely lowering the threshold of increase in absolute serum creatinine and 
      extending the time frame for AKI detection to 7 days. We evaluated the incidence, 
      risk factors, and long-term mortality associated with AKI as classified by the 
      KDIGO definition in a large single center cohort of consecutive STEMI patients. 
      METHODS: We retrospectively studied 2122 consecutive STEMI patients undergoing 
      primary percutaneous coronary intervention (PCI). Recruited patients were 
      admitted between January 2008 and May 2016 to the cardiac intensive care unit 
      with the diagnosis of acute STEMI. We compared the utilization of the KDIGO and 
      consensus criteria for the diagnosis of AKI and its relation to long term 
      mortality. RESULTS: The KDIGO criteria allowed the identification of more 
      patients as having AKI (10.6 vs. 5.6%, p < 0.001) compared to the consensus 
      criteria. Even mild elevation of serum creatinine (>/= 0.3 mg/dL) was associated 
      with a marked increase in all-cause mortality (HR 4.7, 95% CI 3.1-6.43, 
      p < 0.001). Patients with AKI whose renal function resolved prior to hospital 
      discharge still had significantly higher mortality compared to patients with no 
      AKI (23 vs. 8%, HR 3.1, 95% CI 2.09-4.90, p < 0.001). CONCLUSION: KDIGO criteria 
      is more sensitive than the consensus criteria in defining AKI in STEMI patients 
      and identifying populations at risk for long term adverse outcomes.
FAU - Margolis, Gilad
AU  - Margolis G
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, 64239, Tel 
      Aviv, Israel.
FAU - Gal-Oz, Amir
AU  - Gal-Oz A
AD  - Department of Nephrology, Tel-Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
FAU - Letourneau-Shesaf, Sevan
AU  - Letourneau-Shesaf S
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, 64239, Tel 
      Aviv, Israel.
FAU - Khoury, Shafik
AU  - Khoury S
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, 64239, Tel 
      Aviv, Israel.
FAU - Keren, Gad
AU  - Keren G
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, 64239, Tel 
      Aviv, Israel.
FAU - Shacham, Yacov
AU  - Shacham Y
AUID- ORCID: 0000-0003-0805-3185
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, 64239, Tel 
      Aviv, Israel. kobyshacham@gmail.com.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20171128
PL  - Italy
TA  - J Nephrol
JT  - Journal of nephrology
JID - 9012268
RN  - 0 (Contrast Media)
RN  - AYI8EX34EU (Creatinine)
MH  - Acute Kidney Injury/*diagnosis/*epidemiology/etiology/mortality
MH  - Aged
MH  - Aged, 80 and over
MH  - Contrast Media/administration & dosage
MH  - Creatinine/blood
MH  - Female
MH  - Humans
MH  - Hypertension/epidemiology
MH  - Incidence
MH  - Kaplan-Meier Estimate
MH  - Male
MH  - Middle Aged
MH  - Percutaneous Coronary Intervention
MH  - Retrospective Studies
MH  - Risk Factors
MH  - ST Elevation Myocardial 
      Infarction/*complications/mortality/*physiopathology/surgery
MH  - Severity of Illness Index
MH  - Stroke Volume
MH  - Survival Rate
OTO - NOTNLM
OT  - Acute kidney injury
OT  - Contrast induced nephropathy
OT  - Percutaneous coronary intervention
OT  - ST elevation myocardial infarction
EDAT- 2017/12/01 06:00
MHDA- 2019/08/14 06:00
CRDT- 2017/11/30 06:00
PHST- 2017/08/18 00:00 [received]
PHST- 2017/11/03 00:00 [accepted]
PHST- 2017/12/01 06:00 [pubmed]
PHST- 2019/08/14 06:00 [medline]
PHST- 2017/11/30 06:00 [entrez]
AID - 10.1007/s40620-017-0461-3 [pii]
AID - 10.1007/s40620-017-0461-3 [doi]
PST - ppublish
SO  - J Nephrol. 2018 Jun;31(3):423-428. doi: 10.1007/s40620-017-0461-3. Epub 2017 Nov 
      28.