PMID- 29185842 OWN - NLM STAT- MEDLINE DCOM- 20181218 LR - 20181218 IS - 1532-2491 (Electronic) IS - 1082-6084 (Linking) VI - 53 IP - 8 DP - 2018 Jul 3 TI - Characterizing a Hidden Group of At-Risk Drinkers: Epidemiological Profiles of Alcohol-Use Disorder Diagnostic Orphans. PG - 1239-1251 LID - 10.1080/10826084.2017.1402057 [doi] AB - BACKGROUND: Drinkers who report some symptoms of alcohol-use disorder (AUD) but fail to meet full criteria are "diagnostic orphans." To improve risk-reduction efforts, we sought to develop better epidemiologic profiles of this underrecognized subgroup. METHODS: This study estimated the population prevalence and described AUD symptoms of diagnostic orphans using the 2012-2013 National Epidemiological Survey of Alcohol and Related Conditions-III. Multivariate logistic regression was used to model odds of being a diagnostic orphan or meeting mild, moderate, and severe AUD criteria versus no AUD symptoms. Models were adjusted for the complex survey design using sampling weights and survey procedures (e.g., proc surveylogistic). RESULTS: Among drinkers, 14% of men and 11% of women were classified as diagnostic orphans. The most common symptoms were drinking more or for longer periods than intended, wanting or trying unsuccessfully to quit or cut back, and drinking in ways that increased risk of injury. We noted broad similarities between diagnostic orphans and mild/moderate AUD groups. There were no differences in odds of diagnostic orphans status by race/ethnicity; however, female gender was associated with lower odds of diagnostic orphan status and all levels of AUD. Individual history of AUD, family history of problem drinking, concurrent smoking, and concurrent marijuana use were associated with greater odds of problem drinking, with stronger associations as AUD severity increased. CONCLUSIONS: Diagnostic orphans remain a sizeable and overlooked population of problem drinkers. Clarifying the array of symptoms and cooccurring disorders can improve screening and facilitate alcohol risk-reduction intervention efforts. FAU - Gilbert, Paul A AU - Gilbert PA AD - a Department of Community and Behavioral Health , University of Iowa College of Public Health , Iowa City , Iowa , USA. FAU - Marzell, Miesha AU - Marzell M AD - b Department of Social Work , College of Community & Public Affairs, Binghamton University , Binghamton , New York , USA. LA - eng PT - Journal Article DEP - 20171129 PL - England TA - Subst Use Misuse JT - Substance use & misuse JID - 9602153 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Alcoholism/*diagnosis/*epidemiology MH - Female MH - Humans MH - Male MH - Middle Aged MH - Prevalence MH - Risk Factors MH - Socioeconomic Factors MH - Symptom Assessment MH - Young Adult OTO - NOTNLM OT - Black OT - disparities OT - hazardous drinking OT - latino OT - screening OT - women EDAT- 2017/12/01 06:00 MHDA- 2018/12/19 06:00 CRDT- 2017/11/30 06:00 PHST- 2017/12/01 06:00 [pubmed] PHST- 2018/12/19 06:00 [medline] PHST- 2017/11/30 06:00 [entrez] AID - 10.1080/10826084.2017.1402057 [doi] PST - ppublish SO - Subst Use Misuse. 2018 Jul 3;53(8):1239-1251. doi: 10.1080/10826084.2017.1402057. Epub 2017 Nov 29.