PMID- 29193243
OWN - NLM
STAT- MEDLINE
DCOM- 20181217
LR  - 20181217
IS  - 1552-8618 (Electronic)
IS  - 0730-7268 (Linking)
VI  - 37
IP  - 4
DP  - 2018 Apr
TI  - Dioxin-like contaminants are no longer a risk to the American eel (Anguilla 
      rostrata) in Lake Ontario.
PG  - 1061-1070
LID - 10.1002/etc.4033 [doi]
AB  - The embryotoxicity of extracts of American eels (Anguilla rostrata) was measured 
      to determine whether maternally derived contaminants contribute to the declining 
      recruitment of eels to Lake Ontario. Sexually maturing, large yellow and silver 
      eels were sampled in 2007 and 2008 from 5 locations in eastern Canada, including 
      Lake Ontario; positive controls included eels from the Hudson River, United 
      States, and Canal Dessel-Schoten, Belgium (European eel, Anguilla anguilla). 
      Japanese medaka eggs were injected immediately after fertilization with 1 or 
      10 nL of eel extract and, after 12 d, scored for signs of toxicity. Eel extracts 
      did not cause dioxin-like embryotoxicity, reflecting the low concentrations of 
      total dioxin equivalents measured chemically in these same extracts. Embryo 
      mortality and reduced hatching success at high doses of eel extracts may reflect 
      the bioaccumulation of legacy or emerging chemicals of concern. The results were 
      consistent with long-term trends of declining concentrations of persistent 
      organic pollutants (POPs) in tissues of eels and other fish species from Lake 
      Ontario, trends of declining embryotoxicity of eel tissue extracts, and recent 
      increases of recruitment of juvenile eels to Lake Ontario. If dioxin-like 
      compounds contributed in the past to the decline of recruitment and abundance of 
      American eels in Lake Ontario, these data suggest that recruitment should 
      recover, following the same trends as the recovery of lake trout reproduction in 
      Lake Ontario. Environ Toxicol Chem 2018;37:1061-1070. (c) 2017 SETAC.
CI  - (c) 2017 SETAC.
FAU - Hoobin, Sharilyn J
AU  - Hoobin SJ
AD  - Department of Biology, Queen's University, Kingston, Ontario, Canada.
AD  - BluMetric Environmental, The Woolen Mill, Kingston, Ontario, Canada.
FAU - Byer, Jonathan D
AU  - Byer JD
AD  - Department of Chemistry, Queen's University, Kingston, Ontario, Canada.
AD  - Environment and Climate Change Canada, Burlington, Ontario, Canada.
FAU - Alaee, Mehran
AU  - Alaee M
AD  - Environment and Climate Change Canada, Burlington, Ontario, Canada.
FAU - Brown, R Stephen
AU  - Brown RS
AD  - School of Environmental Studies, Queen's University, Kingston, Ontario, Canada.
FAU - Hodson, Peter V
AU  - Hodson PV
AD  - Department of Biology, Queen's University, Kingston, Ontario, Canada.
AD  - School of Environmental Studies, Queen's University, Kingston, Ontario, Canada.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20180109
PL  - United States
TA  - Environ Toxicol Chem
JT  - Environmental toxicology and chemistry
JID - 8308958
RN  - 0 (Dioxins)
RN  - 0 (Polychlorinated Dibenzodioxins)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Anguilla/*physiology
MH  - Animals
MH  - Dioxins/*toxicity
MH  - Embryo, Nonmammalian/drug effects
MH  - Geography
MH  - *Lakes
MH  - Ontario
MH  - Oryzias
MH  - Ovum/drug effects
MH  - Polychlorinated Dibenzodioxins/toxicity
MH  - Reference Standards
MH  - Risk Factors
MH  - Toxicity Tests
MH  - Water Pollutants, Chemical/*toxicity
OTO - NOTNLM
OT  - American eel
OT  - Dioxin-like contaminant
OT  - Embryotoxicity
OT  - Japanese medaka
OT  - Recruitment
EDAT- 2017/12/02 06:00
MHDA- 2018/12/18 06:00
CRDT- 2017/12/02 06:00
PHST- 2017/07/05 00:00 [received]
PHST- 2017/08/04 00:00 [revised]
PHST- 2017/11/03 00:00 [accepted]
PHST- 2017/12/02 06:00 [pubmed]
PHST- 2018/12/18 06:00 [medline]
PHST- 2017/12/02 06:00 [entrez]
AID - 10.1002/etc.4033 [doi]
PST - ppublish
SO  - Environ Toxicol Chem. 2018 Apr;37(4):1061-1070. doi: 10.1002/etc.4033. Epub 2018 
      Jan 9.