PMID- 29194424
OWN - NLM
STAT- MEDLINE
DCOM- 20180726
LR  - 20181113
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 9
IP  - 12
DP  - 2017 Dec 1
TI  - Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management.
LID - 10.3390/nu9121310 [doi]
LID - 1310
AB  - Functional foods contain biologically active ingredients associated with 
      physiological health benefits for preventing and managing chronic diseases, such 
      as type 2 diabetes mellitus (T2DM). A regular consumption of functional foods may 
      be associated with enhanced anti-oxidant, anti-inflammatory, insulin sensitivity, 
      and anti-cholesterol functions, which are considered integral to prevent and 
      manage T2DM. Components of the Mediterranean diet (MD)-such as fruits, 
      vegetables, oily fish, olive oil, and tree nuts-serve as a model for functional 
      foods based on their natural contents of nutraceuticals, including polyphenols, 
      terpenoids, flavonoids, alkaloids, sterols, pigments, and unsaturated fatty 
      acids. Polyphenols within MD and polyphenol-rich herbs-such as coffee, green tea, 
      black tea, and yerba mate-have shown clinically-meaningful benefits on metabolic 
      and microvascular activities, cholesterol and fasting glucose lowering, and 
      anti-inflammation and anti-oxidation in high-risk and T2DM patients. However, 
      combining exercise with functional food consumption can trigger and augment 
      several metabolic and cardiovascular protective benefits, but it is 
      under-investigated in people with T2DM and bariatric surgery patients. Detecting 
      functional food benefits can now rely on an "omics" biological profiling of 
      individuals' molecular, genetics, transcriptomics, proteomics, and metabolomics, 
      but is under-investigated in multi-component interventions. A personalized 
      approach for preventing and managing T2DM should consider biological and 
      behavioral models, and embed nutrition education as part of lifestyle diabetes 
      prevention studies. Functional foods may provide additional benefits in such an 
      approach.
FAU - Alkhatib, Ahmad
AU  - Alkhatib A
AD  - Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait. 
      drahmadalkhatib@gmail.com.
FAU - Tsang, Catherine
AU  - Tsang C
AD  - Faculty of Health and Social Care, Edge Hill University, St. Helens Road, 
      Ormskirk, Lancashire L39 4QP, UK. Tsang@edgehill.ac.uk.
FAU - Tiss, Ali
AU  - Tiss A
AD  - Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait. 
      ali.tiss@dasmaninstitute.org.
FAU - Bahorun, Theeshan
AU  - Bahorun T
AD  - ANDI Centre of Excellence for Biomedical and Biomaterials Research, University of 
      Mauritius, MSIRI Building, Reduit 80837, Mauritius. tbahorun@uom.ac.mu.
FAU - Arefanian, Hossein
AU  - Arefanian H
AD  - Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait. 
      hossein.arefanian@dasmaninstitute.org.
FAU - Barake, Roula
AU  - Barake R
AD  - Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait. 
      roula.barake@dasmaninstitute.org.
FAU - Khadir, Abdelkrim
AU  - Khadir A
AD  - Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait. 
      abdelkrim.khadir@dasmaninstitute.org.
FAU - Tuomilehto, Jaakko
AU  - Tuomilehto J
AD  - Dasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait. 
      jaakko.tuomilehto@dasmaninstitute.org.
AD  - Diabetes Research Group, King Abdulaziz University, P.O. Box 80200, Jeddah 21589, 
      Saudi Arabia. jaakko.tuomilehto@dasmaninstitute.org.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20171201
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
SB  - IM
MH  - Diabetes Mellitus, Type 2/*prevention & control
MH  - Diet, Mediterranean
MH  - *Functional Food
MH  - Humans
MH  - *Life Style
PMC - PMC5748760
OTO - NOTNLM
OT  - Mediterranean diet
OT  - bariatric surgery
OT  - functional food
OT  - green tea
OT  - nutrition counselling
OT  - physical activity
OT  - polyphenols
OT  - type 2 diabetes mellitus
OT  - yerba mate
COIS- No conflict of interest or otherwise is declared as part of this work.
EDAT- 2017/12/02 06:00
MHDA- 2018/07/27 06:00
PMCR- 2017/12/01
CRDT- 2017/12/02 06:00
PHST- 2017/10/31 00:00 [received]
PHST- 2017/11/26 00:00 [revised]
PHST- 2017/11/27 00:00 [accepted]
PHST- 2017/12/02 06:00 [entrez]
PHST- 2017/12/02 06:00 [pubmed]
PHST- 2018/07/27 06:00 [medline]
PHST- 2017/12/01 00:00 [pmc-release]
AID - nu9121310 [pii]
AID - nutrients-09-01310 [pii]
AID - 10.3390/nu9121310 [doi]
PST - epublish
SO  - Nutrients. 2017 Dec 1;9(12):1310. doi: 10.3390/nu9121310.