PMID- 29196573
OWN - NLM
STAT- MEDLINE
DCOM- 20190722
LR  - 20190722
IS  - 1526-632X (Electronic)
IS  - 0028-3878 (Linking)
VI  - 90
IP  - 1
DP  - 2018 Jan 2
TI  - Costs of informal nursing care for patients with neurologic disorders: A 
      systematic review.
PG  - 28-34
LID - 10.1212/WNL.0000000000004763 [doi]
AB  - OBJECTIVE: To systematically review the economic burden of informal nursing care 
      (INC), often called informal care, caused by multiple sclerosis (MS), Parkinson 
      disease (PD), and epilepsy, with special attention to disease severity. METHODS: 
      We systematically searched MEDLINE, PsycINFO, and NHS Economic Evaluation 
      Database for articles on the cost of illness of the diseases specified. Title, 
      abstract, and full-text review were conducted in duplicate by 2 researchers. The 
      distribution of hours and costs of INC were extracted and used to compare the 
      relevance of INC across included diseases and disease severity. RESULTS: 
      Seventy-one studies were included (44 on MS, 17 on PD, and 10 on epilepsy). 
      Studies on epilepsy reported an average of 2.3-54.5 monthly hours of INC per 
      patient. For PD, average values of 42.9-145.9 hours and for MS average values of 
      9.2-249 hours per patient per month were found. In line with utilized hours, 
      costs of INC were lowest for epilepsy (interquartile range [IQR] 229-1,466 
      purchasing power parity US dollars [PPP-USD]) and similar for MS (IQR 
      4,454-11,222 PPP-USD) and PD (IQR 1,440-7,117 PPP-USD). In addition, costs of INC 
      increased with disease severity and accounted for 38% of total health care costs 
      in severe MS stages on average. CONCLUSIONS: The course of diseases and disease 
      severity matter for the amount of INC used by patients. For each of the 
      neurologic disorders, an increase in the costs of INC, due to increasing disease 
      severity, considerably contributes to the rise in total health care costs.
CI  - Copyright (c) 2017 American Academy of Neurology.
FAU - Diederich, Freya
AU  - Diederich F
AD  - From the Department of Health Economics and Health Services Research, Hamburg 
      Center for Health Economics, University Medical Center Hamburg-Eppendorf, 
      Germany. f.diederich@uke.de.
FAU - Konig, Hans-Helmut
AU  - Konig HH
AD  - From the Department of Health Economics and Health Services Research, Hamburg 
      Center for Health Economics, University Medical Center Hamburg-Eppendorf, 
      Germany.
FAU - Mietzner, Claudia
AU  - Mietzner C
AD  - From the Department of Health Economics and Health Services Research, Hamburg 
      Center for Health Economics, University Medical Center Hamburg-Eppendorf, 
      Germany.
FAU - Brettschneider, Christian
AU  - Brettschneider C
AD  - From the Department of Health Economics and Health Services Research, Hamburg 
      Center for Health Economics, University Medical Center Hamburg-Eppendorf, 
      Germany.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Systematic Review
DEP - 20171201
PL  - United States
TA  - Neurology
JT  - Neurology
JID - 0401060
SB  - IM
CIN - Neurology. 2018 Jan 2;90(1):35. PMID: 29196577
MH  - Cost of Illness
MH  - Home Nursing/*economics
MH  - Humans
MH  - Nervous System Diseases/*economics/*therapy
EDAT- 2017/12/03 06:00
MHDA- 2019/07/23 06:00
CRDT- 2017/12/03 06:00
PHST- 2017/03/17 00:00 [received]
PHST- 2017/09/11 00:00 [accepted]
PHST- 2017/12/03 06:00 [pubmed]
PHST- 2019/07/23 06:00 [medline]
PHST- 2017/12/03 06:00 [entrez]
AID - WNL.0000000000004763 [pii]
AID - 10.1212/WNL.0000000000004763 [doi]
PST - ppublish
SO  - Neurology. 2018 Jan 2;90(1):28-34. doi: 10.1212/WNL.0000000000004763. Epub 2017 
      Dec 1.