PMID- 29197198
OWN - NLM
STAT- MEDLINE
DCOM- 20180906
LR  - 20181202
IS  - 0353-5053 (Print)
IS  - 0353-5053 (Linking)
VI  - 29
IP  - 4
DP  - 2017 Dec
TI  - Cardiovascular Disease Risk Factors in Patients with Posttraumatic Stress 
      Disorder (PTSD): A Narrative Review.
PG  - 421-430
LID - 10.24869/psyd.2017.421 [doi]
AB  - Posttraumatic stress disorder (PTSD) is a chronic condition related to severe 
      stress and trauma. There is a mounting evidence about increased prevalence and 
      mortality from cardiovascular diseases (CVD) in patients with PTSD. This review 
      summarizes the current data on possible relations between PTSD and increased 
      risks of CVD, including biological, psychological and behavioral factors. 
      Biological factors refer to increased prevalence of metabolic syndrome (MetS), 
      hypertension, elevation of pro-inflammatory cytokines and homocysteine levels. 
      Peripheral Brain-derived neurotropic factor (BDNF), serum N-terminal pro-brain 
      natriuretic peptide (NT-proBNP) and quantitative electroencephalogram (qEEG) are 
      promising surrogate markers of increased cardiovascular risk. Among psychological 
      factors, some personality traits, such as neuroticism and trait 
      impulsivity/hostility, contribute to the development of PTSD, and are associated 
      with general cardiovascular distress. Recently, type-D (distressed) personality 
      is usually investigated in relation to cardiovascular morbidity, but in 
      populations other than PTSD patients. Behavioral factors refer to unhealthy 
      life-styles, encompassing high smoking rate, drug substances abuse and addiction, 
      physical inactivity and unhealthy diet. The relationships among all these factors 
      are complex and yet incompletely taken into consideration. Because of a high 
      prevalence of CVD in patients with PTSD, there is a strong need for a more 
      intensive focus on this vulnerable population in both primary and secondary 
      cardiovascular prevention as well as in effective treatment possibilities.
FAU - Sagud, Marina
AU  - Sagud M
AD  - School of Medicine, University of Zagreb, Department of Psychiatry, University 
      Hospital Center Zagreb, Kispaticeva 12, 10 000 Zagreb, Croatia, Croatia.
FAU - Jaksic, Nenad
AU  - Jaksic N
FAU - Vuksan-Cusa, Bjanka
AU  - Vuksan-Cusa B
FAU - Loncar, Mladen
AU  - Loncar M
FAU - Loncar, Ivana
AU  - Loncar I
FAU - Peles, Alma Mihaljevic
AU  - Peles AM
FAU - Milicic, Davor
AU  - Milicic D
FAU - Jakovljevic, Miro
AU  - Jakovljevic M
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Croatia
TA  - Psychiatr Danub
JT  - Psychiatria Danubina
JID - 9424753
RN  - 0 (Peptide Fragments)
RN  - 0 (pro-brain natriuretic peptide (1-76))
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
MH  - Cardiovascular Diseases/*diagnosis/mortality/*psychology
MH  - Character
MH  - Female
MH  - Health Behavior
MH  - Humans
MH  - Metabolic Syndrome/diagnosis/mortality/psychology
MH  - Natriuretic Peptide, Brain
MH  - Peptide Fragments
MH  - Resilience, Psychological
MH  - Risk
MH  - Risk Factors
MH  - Stress Disorders, Post-Traumatic/*diagnosis/mortality/*psychology
MH  - Survival Rate
MH  - Type D Personality
EDAT- 2017/12/03 06:00
MHDA- 2018/09/07 06:00
CRDT- 2017/12/03 06:00
PHST- 2017/12/03 06:00 [entrez]
PHST- 2017/12/03 06:00 [pubmed]
PHST- 2018/09/07 06:00 [medline]
AID - 10.24869/psyd.2017.421 [doi]
PST - ppublish
SO  - Psychiatr Danub. 2017 Dec;29(4):421-430. doi: 10.24869/psyd.2017.421.