PMID- 29199164 OWN - NLM STAT- MEDLINE DCOM- 20180724 LR - 20180724 IS - 2148-5607 (Electronic) IS - 1300-4948 (Linking) VI - 28 IP - Suppl 1 DP - 2017 Dec TI - Does the treatment of proton pump inhibitors reduce dysplasia or adenocarcinoma development in Barrett's esophagus? PG - S31-S32 LID - 10.5152/tjg.2017.09 [doi] AB - Besides reducing the reflux symptoms, the benefit of proton pump inhibitors (PPI) in the treatment of Barrett's esophagus (BE) is not exactly known. The data in the literature show that although the PPI treatment does not reduce the Barrett's segment length, it can reduce dysplasia or the development of early-stage adenocarcinoma (odds ratio (OR): 0.46). Therefore, treatments with PPI may be considered in patients with a diagnosis of BE and at a high risk of adenocarcinoma, even though they are not symptomatic. FAU - Akin, Hakan AU - Akin H FAU - Aydin, Yucel AU - Aydin Y LA - eng PT - Journal Article PT - Review PL - Turkey TA - Turk J Gastroenterol JT - The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology JID - 9515841 RN - 0 (Proton Pump Inhibitors) RN - Adenocarcinoma Of Esophagus SB - IM MH - Adenocarcinoma/etiology/*prevention & control MH - Adult MH - Barrett Esophagus/complications/*drug therapy/pathology MH - Esophageal Neoplasms/etiology/*prevention & control MH - Esophagus/*pathology MH - Female MH - Humans MH - Hyperplasia/etiology/prevention & control MH - Male MH - Middle Aged MH - Proton Pump Inhibitors/*therapeutic use MH - Treatment Outcome EDAT- 2017/12/05 06:00 MHDA- 2018/07/25 06:00 CRDT- 2017/12/05 06:00 PHST- 2017/12/05 06:00 [entrez] PHST- 2017/12/05 06:00 [pubmed] PHST- 2018/07/25 06:00 [medline] AID - 10.5152/tjg.2017.09 [doi] PST - ppublish SO - Turk J Gastroenterol. 2017 Dec;28(Suppl 1):S31-S32. doi: 10.5152/tjg.2017.09.