PMID- 29199171
OWN - NLM
STAT- MEDLINE
DCOM- 20180724
LR  - 20180724
IS  - 2148-5607 (Electronic)
IS  - 1300-4948 (Linking)
VI  - 28
IP  - Suppl 1
DP  - 2017 Dec
TI  - Gastroesophageal reflux disease and the relationship with Helicobacter pylori.
PG  - S61-S67
LID - 10.5152/tjg.2017.16 [doi]
AB  - After Helicobacter pylori was identified, and its relationship with peptic ulcer 
      disease was exactly shown, the relationship of this bacterium with 
      gastroesophageal reflux disease (GERD) gained momentum and discussions continue 
      to this day. We reviewed the literature for the relationship between H. pylori 
      and GERD. According to the existing data, there is no relationship between GERD 
      and H. pylori presence. Successful eradication therapy does not have an impact on 
      the emergence or exacerbation of GERD. However Barrett's esophagus and esophageal 
      adenocarcinoma are less frequent, especially in the presence of CagA positive H. 
      pylori infections. Long-term use of proton pump inhibitor (PPI) may have an 
      impact on the development of atrophy and/or intestinal metaplasia in H. pylori 
      positive patients; therefore, H. pylori eradication is recommended in patients 
      that should use long-term PPI. As a conclusion, H. pylori screening and the 
      eradication decision should be independent of GERD, except for patients that will 
      use long-term PPI.
FAU - Mungan, Zeynel
AU  - Mungan Z
AD  - Department of Gastroenterology, Koc University School of Medicine, Istanbul, 
      Turkey
FAU - Pinarbasi Simsek, Binnur
AU  - Pinarbasi Simsek B
AD  - Department of Gastroenterology, Istinye University School of Medicine, Istanbul, 
      Turkey
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Turkey
TA  - Turk J Gastroenterol
JT  - The Turkish journal of gastroenterology : the official journal of Turkish Society 
      of Gastroenterology
JID - 9515841
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Anti-Bacterial Agents/*therapeutic use
MH  - Gastroesophageal Reflux/*microbiology
MH  - Helicobacter Infections/*drug therapy/microbiology
MH  - *Helicobacter pylori
MH  - Humans
MH  - Proton Pump Inhibitors/*therapeutic use
EDAT- 2017/12/05 06:00
MHDA- 2018/07/25 06:00
CRDT- 2017/12/05 06:00
PHST- 2017/12/05 06:00 [entrez]
PHST- 2017/12/05 06:00 [pubmed]
PHST- 2018/07/25 06:00 [medline]
AID - 10.5152/tjg.2017.16 [doi]
PST - ppublish
SO  - Turk J Gastroenterol. 2017 Dec;28(Suppl 1):S61-S67. doi: 10.5152/tjg.2017.16.