PMID- 29200146 OWN - NLM STAT- MEDLINE DCOM- 20190319 LR - 20190319 IS - 1536-3678 (Electronic) IS - 1077-4114 (Linking) VI - 40 IP - 5 DP - 2018 Jul TI - Successful Treatment of Mediastinal gammadelta T-Cell Lymphoblastic Lymphoma in a 3-Year-Old Girl by Allogeneic Cord Blood Transplantation. PG - e311-e314 LID - 10.1097/MPH.0000000000000999 [doi] AB - A 3-year-old girl presenting with a huge mediastinal tumor and massive pleural effusion, was diagnosed with stage III gammadelta T-cell lymphoblastic lymphoma (gammadelta T-LBL) by flow cytometry of effusion cells. Four courses of chemotherapy achieved complete remission, and 5/6 HLA allele-matched cord blood transplantation was performed with success. The patient remains in first complete remission >16 months after transplantation. gammadelta T-LBL is very rare, especially that of mediastinal origin, and is acknowledged as having an extremely poor clinical outcome. The present case study is the first to report the successful treatment of mediastinal gammadelta T-LBL in a toddler. FAU - Hori, Daiki AU - Hori D AD - Department of Hematology/Oncology for Children and Adolescents, Sapporo Hokuyu Hospital, Sapporo. FAU - Kobayashi, Ryoji AU - Kobayashi R AD - Department of Hematology/Oncology for Children and Adolescents, Sapporo Hokuyu Hospital, Sapporo. FAU - Suzuki, Daisuke AU - Suzuki D AD - Department of Hematology/Oncology for Children and Adolescents, Sapporo Hokuyu Hospital, Sapporo. FAU - Sano, Hirozumi AU - Sano H AD - Department of Hematology/Oncology for Children and Adolescents, Sapporo Hokuyu Hospital, Sapporo. FAU - Kiyokawa, Nobutaka AU - Kiyokawa N AD - Department of Pediatric Hematology and Oncology Research, National Research Institute for Child Health and Development, Tokyo, Japan. FAU - Kobayashi, Kunihiko AU - Kobayashi K AD - Department of Hematology/Oncology for Children and Adolescents, Sapporo Hokuyu Hospital, Sapporo. LA - eng PT - Case Reports PT - Journal Article PL - United States TA - J Pediatr Hematol Oncol JT - Journal of pediatric hematology/oncology JID - 9505928 RN - 0 (Receptors, Antigen, T-Cell, gamma-delta) SB - IM MH - Allografts MH - Child, Preschool MH - Cord Blood Stem Cell Transplantation MH - Female MH - Humans MH - Mediastinal Neoplasms/*therapy MH - Pleural Effusion, Malignant/*therapy MH - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*therapy MH - *Receptors, Antigen, T-Cell, gamma-delta EDAT- 2017/12/05 06:00 MHDA- 2019/03/20 06:00 CRDT- 2017/12/05 06:00 PHST- 2017/12/05 06:00 [pubmed] PHST- 2019/03/20 06:00 [medline] PHST- 2017/12/05 06:00 [entrez] AID - 10.1097/MPH.0000000000000999 [doi] PST - ppublish SO - J Pediatr Hematol Oncol. 2018 Jul;40(5):e311-e314. doi: 10.1097/MPH.0000000000000999.