PMID- 29200768
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1013-9087 (Print)
IS  - 2005-3894 (Electronic)
IS  - 1013-9087 (Linking)
VI  - 29
IP  - 6
DP  - 2017 Dec
TI  - Congenital Non-Neural Granular Cell Tumor Mimicking Nevus Lipomatosus 
      Superficialis.
PG  - 776-778
LID - 10.5021/ad.2017.29.6.776 [doi]
AB  - A 4-month-old infant presented with asymptomatic soft nodules on his right 
      forearm, which had developed since birth. On the suspicion of nevus lipomatosus 
      superficialis (NLS), biopsy was performed. Histopathologic findings showed 
      monomorphic polygonal cells with abundant granular cytoplasm. Immunohistochemical 
      stains for CD68 and vimentin were strongly positive, but were negative for S-100 
      protein. Based on the pathologic findings, the patient was diagnosed as 
      non-neural granular cell tumor (NN-GCT). GCT can be divided into conventional and 
      non-neural GCT by immunoreactivity for S-100 protein. NN-GCT is typically 
      manifested as a well-circumscribed, papulo-nodular dermal mass, and is known to 
      occur in a younger group than does in conventional GCT, but is rare among 
      children. To our knowledge, there have been no case reports of NN-GCT which 
      appeared at birth and presented as grouped nodules. Therefore, we report this 
      interesting case of congenital NN-GCT clinically mimicking NLS.
FAU - Park, Jun Yeong
AU  - Park JY
AD  - Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, 
      Korea.
FAU - Kwon, Won Joo
AU  - Kwon WJ
AD  - Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, 
      Korea.
FAU - Park, Bok Won
AU  - Park BW
AD  - Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, 
      Korea.
FAU - Cho, Eun Byul
AU  - Cho EB
AD  - Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, 
      Korea.
FAU - Park, Eun Joo
AU  - Park EJ
AD  - Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, 
      Korea.
FAU - Kim, Kwang Ho
AU  - Kim KH
AD  - Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, 
      Korea.
FAU - Kim, Kwang Joong
AU  - Kim KJ
AD  - Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, 
      Korea.
LA  - eng
PT  - Case Reports
DEP - 20171030
PL  - Korea (South)
TA  - Ann Dermatol
JT  - Annals of dermatology
JID - 8916577
PMC - PMC5705361
OTO - NOTNLM
OT  - CD68
OT  - Granular cell tumor
OT  - Nevus lipomatosus superficialis
OT  - S100 proteins
OT  - Vimentin
COIS- CONFLICTS OF INTEREST: The authors have nothing to disclose.
EDAT- 2017/12/05 06:00
MHDA- 2017/12/05 06:01
PMCR- 2017/12/01
CRDT- 2017/12/05 06:00
PHST- 2016/08/01 00:00 [received]
PHST- 2016/11/23 00:00 [revised]
PHST- 2016/12/16 00:00 [accepted]
PHST- 2017/12/05 06:00 [entrez]
PHST- 2017/12/05 06:00 [pubmed]
PHST- 2017/12/05 06:01 [medline]
PHST- 2017/12/01 00:00 [pmc-release]
AID - 10.5021/ad.2017.29.6.776 [doi]
PST - ppublish
SO  - Ann Dermatol. 2017 Dec;29(6):776-778. doi: 10.5021/ad.2017.29.6.776. Epub 2017 
      Oct 30.