PMID- 29213584
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231112
IS  - 1980-5764 (Print)
IS  - 1980-5764 (Linking)
VI  - 2
IP  - 4
DP  - 2008 Oct-Dec
TI  - Behavioral and psychological symptoms in dementia is not a unitary concept: A 
      critical review with emphasis on Alzheimer's disease.
PG  - 272-277
LID - 10.1590/S1980-57642009DN20400007 [doi]
AB  - Behavioral and Psychological Symptoms of Dementia (BPSD) is an important feature 
      of dementia. However, this definition comprises a large array of symptoms and 
      syndromes. This hampers understanding of the behavior of patients with dementia 
      and the devising of strategies to ameliorate these symptoms. OBJECTIVES: This 
      review aimed to describe the main factors and syndromes that comprise BPSD, as 
      well as neuroimaging, psychopharmacological, and genetic data derived from 
      studies of these factors. METHODS: A search on the Medline, Scielo, and ISI 
      databases was performed using the keyword BPSD for articles published within the 
      last five years. Selected publications were favored, so this review should not be 
      regarded as a systematic study on the subject. RESULTS: The main factors and 
      syndromes comprising BPSD were identified, namely psychosis, depression, and 
      activity. Different ways of clustering symptoms were considered. The main 
      manifestations of psychosis, apathy and depression were focused, relating 
      phenomenology to neuroimaging and pharmacological issues. CONCLUSIONS: BPSD is a 
      heterogeneous array of symptoms which can be better understood as clusters. At 
      least three factors can be separated in BSPD, namely psychosis, depression, and 
      activity. This division may offer guidance to clinicians regarding treatment 
      management and follow up of the chosen therapeutic strategy.
FAU - Laks, Jerson
AU  - Laks J
AD  - Center for Alzheimer's Disease/ Institute of Psychiatry/Federal University of Rio 
      de Janeiro; School of Medical Sciences, State University of Rio de Janeiro.
FAU - Engelhardt, Eliasz
AU  - Engelhardt E
AD  - Institute of Neurology Deolindo Couto of the Federal University of Rio de 
      Janeiro.
LA  - eng
PT  - Journal Article
PL  - Brazil
TA  - Dement Neuropsychol
JT  - Dementia & neuropsychologia
JID - 101506587
PMC - PMC5619079
OTO - NOTNLM
OT  - BPSD
OT  - apathy
OT  - dementia
OT  - depression
OT  - elderly
OT  - psychosis
EDAT- 2008/10/01 00:00
MHDA- 2008/10/01 00:01
PMCR- 2008/10/01
CRDT- 2017/12/08 06:00
PHST- 2017/12/08 06:00 [entrez]
PHST- 2008/10/01 00:00 [pubmed]
PHST- 2008/10/01 00:01 [medline]
PHST- 2008/10/01 00:00 [pmc-release]
AID - 10.1590/S1980-57642009DN20400007 [doi]
PST - ppublish
SO  - Dement Neuropsychol. 2008 Oct-Dec;2(4):272-277. doi: 
      10.1590/S1980-57642009DN20400007.