PMID- 29213966
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220311
IS  - 1980-5764 (Print)
IS  - 1980-5764 (Linking)
VI  - 9
IP  - 3
DP  - 2015 Jul-Sep
TI  - Neuropsychiatric symptoms in Vascular Cognitive Impairment: a systematic review.
PG  - 230-236
LID - 10.1590/1980-57642015DN93000004 [doi]
AB  - Neuropsychiatric symptoms or Behavioral and Psychological Symptoms of Dementia 
      (BPSD) are common and invariably appear at some point during the course of the 
      disease, mediated both by cerebrovascular disease and neurodegenerative 
      processes. Few studies have compared the profiles of BPSD in Vascular Cognitive 
      Impairment (VCI) of different subtypes (subcortical or cortical) and clinical 
      stages (Vascular Cognitive Impairment No Dementia [VaCIND] and Vascular Dementia 
      [VaD]). OBJECTIVE: To review the BPSD associated with different subtypes and 
      stages of VCI using the Neuropsychiatric Inventory (NPI). METHODS: Medline, 
      Scielo and Lilacs databases were searched for the period January 2000 to December 
      2014, with the key words: "BPSD AND Vascular Dementia, "NPI AND Vascular 
      Dementia" and "NPI AND VCI. Qualitative analysis was performed on studies 
      evaluating BPSD in VCI, using the Neuropsychiatric Inventory (NPI). RESULTS: A 
      total of 82 studies were retrieved of which 13 were eligible and thus included. 
      Among the articles selected, 4 compared BPSD in Subcortical Vascular Dementia 
      (SVaD) versus Cortical-Subcortical Vascular Dementia (CSVaD), 3 involved 
      comparisons between SVaD and VaCIND, 1 study analyzed differences between CSVaD 
      and VaCIND, while 5 studies assessed BPSD in CSVaD. Subcortical and 
      Cortical-Subcortical VaD were associated predominantly with Apathy and 
      Depression. VaCIND may present fewer behavioral symptoms than VaD. CONCLUSION: 
      The profile of BPSD differs for different stages of VCI. Determining the most 
      prevalent BPSD in VCI subtypes might be helpful for improving early diagnosis and 
      management of these symptoms.
FAU - Tiel, Chan
AU  - Tiel C
AD  - Instituto de Neurologia Deolindo Couto, Setor de Neurologia Cognitiva e do 
      Comportamento-INDC-CDA/IPUB, UFRJ, Rio de Janeiro RJ, Brazil.
FAU - Sudo, Felipe Kenji
AU  - Sudo FK
AD  - Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro (UFRJ), Rio de 
      Janeiro RJ, Brazil.
FAU - Alves, Gilberto Sousa
AU  - Alves GS
AD  - Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro (UFRJ), Rio de 
      Janeiro RJ, Brazil.
AD  - Departamento de Medicina Clinica, Universidade Federal do Ceara, Fortaleza CE, 
      Brazil.
FAU - Ericeira-Valente, Letice
AU  - Ericeira-Valente L
AD  - Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro (UFRJ), Rio de 
      Janeiro RJ, Brazil.
FAU - Moreira, Denise Madeira
AU  - Moreira DM
AD  - Servico de Radiologia, Instituto de Neurologia Deolindo Couto (UFRJ); Hospital 
      Pro-Cardiaco, Rio de Janeiro RJ, Brazil.
FAU - Laks, Jerson
AU  - Laks J
AD  - Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro (UFRJ), Rio de 
      Janeiro RJ, Brazil.
AD  - Universidade do Estado do Rio de Janeiro, Rio de Janeiro RJ, Brazil.
FAU - Engelhardt, Eliasz
AU  - Engelhardt E
AD  - Instituto de Neurologia Deolindo Couto, Setor de Neurologia Cognitiva e do 
      Comportamento-INDC-CDA/IPUB, UFRJ, Rio de Janeiro RJ, Brazil.
LA  - eng
PT  - Journal Article
PL  - Brazil
TA  - Dement Neuropsychol
JT  - Dementia & neuropsychologia
JID - 101506587
PMC - PMC5619363
OTO - NOTNLM
OT  - Alzheimer's disease
OT  - BPSD
OT  - NPI
OT  - Vascular Cognitive Impairment
OT  - Vascular Dementia
OT  - neuropsychiatric symptoms
COIS- Disclosure: The authors report no conflits of interest.
EDAT- 2015/07/01 00:00
MHDA- 2015/07/01 00:01
PMCR- 2015/07/01
CRDT- 2017/12/08 06:00
PHST- 2017/12/08 06:00 [entrez]
PHST- 2015/07/01 00:00 [pubmed]
PHST- 2015/07/01 00:01 [medline]
PHST- 2015/07/01 00:00 [pmc-release]
AID - 10.1590/1980-57642015DN93000004 [doi]
PST - ppublish
SO  - Dement Neuropsychol. 2015 Jul-Sep;9(3):230-236. doi: 
      10.1590/1980-57642015DN93000004.