PMID- 29216586
OWN - NLM
STAT- MEDLINE
DCOM- 20180130
LR  - 20201209
IS  - 1873-264X (Electronic)
IS  - 0731-7085 (Linking)
VI  - 150
DP  - 2018 Feb 20
TI  - Non-ionic detergent Triton X-114 Based vortex- synchronized matrix solid-phase 
      dispersion method for the simultaneous determination of six compounds with 
      various polarities from Forsythiae Fructus by ultra high-performance liquid 
      chromatography.
PG  - 59-66
LID - S0731-7085(17)32774-7 [pii]
LID - 10.1016/j.jpba.2017.12.003 [doi]
AB  - A simple nonionic detergent - based vortex- synchronized matrix solid-phase 
      dispersion (ND-VSMSPD) method was developed to extract bioactive compounds in 
      Forsythiae Fructus coupled with ultra high-performance liquid chromatography 
      (UHPLC). Nonionic detergent Triton 114 was firstly used as a green elution 
      reagent in vortex- synchronized MSPD procedure. The optimum parameters were 
      investigated to attain the best results, including Florisil as sorbent, 2mL 10% 
      (v/v) nonionic detergent Triton X-114 as the elution reagent, 1:1 of 
      sample/sorbent ratio, grinding for 3min, and whirling for 2min. The recoveries of 
      the six compounds in Forsythiae Fructus were in the range of 95-104% (RSD <4.6%) 
      and the method displayed a good linearity within the range of 0.08-20mugmL(-1) for 
      caffeic acid, 0.6-150mugmL(-1) for forsythoside A, 0.4-100mugmL(-1) phillyrin, 
      0.2-50mugmL(-1) for quercetin, isorhamnetin and arctigenin (r>/=0.999). It was 
      proved that the extraction yields of almost all compounds attained by the 
      established vortex- synchronized MSPD, which required lower sample, reagent and 
      time, were higher than the normal MSPD and the traditional ultrasonic-assisted 
      extraction. Consequently, this developed vortex- synchronized MSPD coupled with 
      simple UHPLC method could be efficiently applies to extract and analyze the 
      target compounds in real Forsythiae Fructus samples.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Du, Kunze
AU  - Du K
AD  - Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of 
      Traditional Chinese Medicine, Tianjin, 300193, China; Key Laboratory of Formula 
      of Traditional Chinese Medicine (Tianjin University of Traditional Chinese 
      Medicine), Ministry of Education, Tianjin, 300193, China.
FAU - Li, Jin
AU  - Li J
AD  - Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of 
      Traditional Chinese Medicine, Tianjin, 300193, China; Key Laboratory of Formula 
      of Traditional Chinese Medicine (Tianjin University of Traditional Chinese 
      Medicine), Ministry of Education, Tianjin, 300193, China.
FAU - Tian, Fei
AU  - Tian F
AD  - Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of 
      Traditional Chinese Medicine, Tianjin, 300193, China; Key Laboratory of Formula 
      of Traditional Chinese Medicine (Tianjin University of Traditional Chinese 
      Medicine), Ministry of Education, Tianjin, 300193, China.
FAU - Chang, Yan-Xu
AU  - Chang YX
AD  - Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of 
      Traditional Chinese Medicine, Tianjin, 300193, China; Key Laboratory of Formula 
      of Traditional Chinese Medicine (Tianjin University of Traditional Chinese 
      Medicine), Ministry of Education, Tianjin, 300193, China. Electronic address: 
      Tcmcyx@126.com.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20171205
PL  - England
TA  - J Pharm Biomed Anal
JT  - Journal of pharmaceutical and biomedical analysis
JID - 8309336
RN  - 0 (Detergents)
RN  - 0 (Plant Extracts)
RN  - 3WJQ0SDW1A (Polyethylene Glycols)
RN  - 9002-93-1 (Octoxynol)
RN  - 9036-19-5 (Nonidet P-40)
SB  - IM
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Detergents/chemistry
MH  - Forsythia/*chemistry
MH  - Fruit
MH  - Octoxynol
MH  - Plant Extracts/analysis/*chemistry
MH  - Polyethylene Glycols/*chemistry
MH  - Solid Phase Extraction/methods
MH  - Time Factors
OTO - NOTNLM
OT  - Forsythiae Fructus
OT  - Nonionic detergent
OT  - Ultra high-performance liquid chromatography
OT  - Vortex- synchronized matrix solid-phase dispersion
EDAT- 2017/12/08 06:00
MHDA- 2018/01/31 06:00
CRDT- 2017/12/08 06:00
PHST- 2017/11/09 00:00 [received]
PHST- 2017/11/30 00:00 [revised]
PHST- 2017/12/02 00:00 [accepted]
PHST- 2017/12/08 06:00 [pubmed]
PHST- 2018/01/31 06:00 [medline]
PHST- 2017/12/08 06:00 [entrez]
AID - S0731-7085(17)32774-7 [pii]
AID - 10.1016/j.jpba.2017.12.003 [doi]
PST - ppublish
SO  - J Pharm Biomed Anal. 2018 Feb 20;150:59-66. doi: 10.1016/j.jpba.2017.12.003. Epub 
      2017 Dec 5.