PMID- 29219149
OWN - NLM
STAT- MEDLINE
DCOM- 20190708
LR  - 20220410
IS  - 1759-5037 (Electronic)
IS  - 1759-5029 (Linking)
VI  - 14
IP  - 2
DP  - 2018 Feb
TI  - Global aetiology and epidemiology of type 2 diabetes mellitus and its 
      complications.
PG  - 88-98
LID - 10.1038/nrendo.2017.151 [doi]
AB  - Globally, the number of people with diabetes mellitus has quadrupled in the past 
      three decades, and diabetes mellitus is the ninth major cause of death. About 1 
      in 11 adults worldwide now have diabetes mellitus, 90% of whom have type 2 
      diabetes mellitus (T2DM). Asia is a major area of the rapidly emerging T2DM 
      global epidemic, with China and India the top two epicentres. Although genetic 
      predisposition partly determines individual susceptibility to T2DM, an unhealthy 
      diet and a sedentary lifestyle are important drivers of the current global 
      epidemic; early developmental factors (such as intrauterine exposures) also have 
      a role in susceptibility to T2DM later in life. Many cases of T2DM could be 
      prevented with lifestyle changes, including maintaining a healthy body weight, 
      consuming a healthy diet, staying physically active, not smoking and drinking 
      alcohol in moderation. Most patients with T2DM have at least one complication, 
      and cardiovascular complications are the leading cause of morbidity and mortality 
      in these patients. This Review provides an updated view of the global 
      epidemiology of T2DM, as well as dietary, lifestyle and other risk factors for 
      T2DM and its complications.
FAU - Zheng, Yan
AU  - Zheng Y
AD  - State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan 
      University, 2005 Songhu Road, Shanghai, China.
AD  - Department of Nutrition, Harvard T.H. Chan School of Public Health, 2005 Songhu 
      Road, Shanghai, China.
FAU - Ley, Sylvia H
AU  - Ley SH
AD  - Department of Nutrition, Harvard T.H. Chan School of Public Health, 2005 Songhu 
      Road, Shanghai, China.
AD  - Channing Division of Network Medicine, Department of Medicine, Brigham and 
      Women's Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, 
      Massachusetts 02115, USA.
FAU - Hu, Frank B
AU  - Hu FB
AD  - Department of Nutrition, Harvard T.H. Chan School of Public Health, 2005 Songhu 
      Road, Shanghai, China.
AD  - Department of Epidemiology, Harvard T.H. Chan School of Public Health, 665 
      Huntington Avenue, Boston, Massachusetts 02115, USA.
AD  - Channing Division of Network Medicine, Department of Medicine, Brigham and 
      Women's Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, 
      Massachusetts 02115, USA.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20171208
PL  - England
TA  - Nat Rev Endocrinol
JT  - Nature reviews. Endocrinology
JID - 101500078
SB  - IM
MH  - *Diabetes Complications/epidemiology/etiology/prevention & control
MH  - Diabetes Mellitus, Type 2/*epidemiology/etiology/therapy
MH  - *Diet
MH  - *Disease Management
MH  - Global Health
MH  - Humans
MH  - *Life Style
MH  - Morbidity/trends
MH  - Risk Factors
EDAT- 2017/12/09 06:00
MHDA- 2019/07/10 06:00
CRDT- 2017/12/09 06:00
PHST- 2017/12/09 06:00 [pubmed]
PHST- 2019/07/10 06:00 [medline]
PHST- 2017/12/09 06:00 [entrez]
AID - nrendo.2017.151 [pii]
AID - 10.1038/nrendo.2017.151 [doi]
PST - ppublish
SO  - Nat Rev Endocrinol. 2018 Feb;14(2):88-98. doi: 10.1038/nrendo.2017.151. Epub 2017 
      Dec 8.