PMID- 29219853
OWN - NLM
STAT- Publisher
LR  - 20240227
IS  - 1674-8301 (Print)
IS  - 2352-4685 (Electronic)
IS  - 1674-8301 (Linking)
VI  - 32
IP  - 1
DP  - 2017 Nov 1
TI  - Effects of a soybean milk product on feto-neonatal development in rats.
PG  - 51-7
LID - 10.7555/JBR.31.20170067 [doi]
AB  - Since estrogenic pollutants and phytoestrogens can cause the disorder of the 
      reproductive system, the effects of a soybean milk product (Vegemil((R)) containing 
      162 ppm isoflavones) on the feto-neonatal development, including male 
      reproductive function, were investigated. Pregnant rats were fed the soybean milk 
      (5% or 100% in drinking water) from gestational day (GD) 6 to parturition or to 
      post-natal day (PND) 56. Specifically, the rats were divided into 4 groups: the 
      control group (drinking water), the GD5% group (5% soybean milk during only the 
      GD period), the GD-PND5% group (5% soybean milk during the GD and PND periods), 
      and the GD-PND100% group (100% soybean milk instead of water during the GD and 
      PND periods). During the gestational, lactational, and developmental periods, the 
      reproductive and developmental parameters of dams and offspring were observed. 
      Feeding soybean milk did not affect the birth and physical development of both 
      male and female offspring. At PND57, the weights of the testes and epididymides 
      of F1 males significantly increased by feeding a high concentration of the 
      soybean milk (GD-PND100%). In addition, feeding of the soybean milk during both 
      the GD and PND periods (GD-PND5% and GD-PND100%) enhanced the sperm counts and 
      motility. The results indicate that soybean milk is safe for embryos, fetuses, 
      and offspring, and improves the post-generational development of male 
      reproductive function.
FAU - Suk An, Eun
AU  - Suk An E
AD  - College of Veterinary Medicine and Veterinary Medical Center, Chungbuk National 
      University, Cheongju 28644, Republic of Korea.
FAU - Park, Dongsun
AU  - Park D
AD  - College of Veterinary Medicine and Veterinary Medical Center, Chungbuk National 
      University, Cheongju 28644, Republic of Korea.
FAU - Ban, Young-Hwan
AU  - Ban YH
AD  - College of Veterinary Medicine and Veterinary Medical Center, Chungbuk National 
      University, Cheongju 28644, Republic of Korea.
FAU - Jieun, Choi
AU  - Jieun C
AD  - College of Veterinary Medicine and Veterinary Medical Center, Chungbuk National 
      University, Cheongju 28644, Republic of Korea.
FAU - Seo, Da Woom
AU  - Seo DW
AD  - College of Veterinary Medicine and Veterinary Medical Center, Chungbuk National 
      University, Cheongju 28644, Republic of Korea.
FAU - Bok Lee, Yoon
AU  - Bok Lee Y
AD  - Central Research Institute, Dr. Chung's Food Co. Ltd., Cheongju 28446, Republic 
      of Korea.
FAU - Shon, Mi Yae
AU  - Shon MY
AD  - International Ginseng and Herb Research Institute, Geumsan 312804, Republic of 
      Korea.
FAU - Choi, Ehn-Kyoung
AU  - Choi EK
AD  - College of Veterinary Medicine and Veterinary Medical Center, Chungbuk National 
      University, Cheongju 28644, Republic of Korea.
FAU - Kim, Yun-Bae
AU  - Kim YB
AD  - College of Veterinary Medicine and Veterinary Medical Center, Chungbuk National 
      University, Cheongju 28644, Republic of Korea.
LA  - eng
PT  - Journal Article
DEP - 20171101
PL  - China
TA  - J Biomed Res
JT  - Journal of biomedical research
JID - 101551157
PMC - PMC5956258
EDAT- 2017/12/09 06:00
MHDA- 2017/12/09 06:00
PMCR- 2018/01/26
CRDT- 2017/12/09 06:00
PHST- 2017/12/09 06:00 [entrez]
PHST- 2017/12/09 06:00 [pubmed]
PHST- 2017/12/09 06:00 [medline]
PHST- 2018/01/26 00:00 [pmc-release]
AID - JBR-2017-0279 [pii]
AID - 10.7555/JBR.31.20170067 [doi]
PST - aheadofprint
SO  - J Biomed Res. 2017 Nov 1;32(1):51-7. doi: 10.7555/JBR.31.20170067.