PMID- 29225978 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 2090-6501 (Print) IS - 2090-651X (Electronic) IS - 2090-651X (Linking) VI - 2017 DP - 2017 TI - Coexistence of GH-Producing Pituitary Macroadenoma and Meningioma in a Patient with Multiple Endocrine Neoplasia Type 1 with Hyperglycemia and Ketosis as First Clinical Sign. PG - 2390797 LID - 10.1155/2017/2390797 [doi] LID - 2390797 AB - We present the clinical case of a patient who was admitted with an onset of diabetes mellitus (DM) with associated ketosis and whose clinical, hormonal, and radiological evolution revealed the presence of primary hyperparathyroidism, pancreatic neuroendocrine tumor, and GH-producing pituitary macroadenoma in the context of multiple endocrine neoplasia type 1 (MEN1). DM is relatively common in cases of acromegaly, but it is not generally associated with ketosis. Simultaneously, the patient presented a meningioma, which is associated with pituitary macroadenoma only in extremely rare cases. FAU - Herrero-Ruiz, A AU - Herrero-Ruiz A AUID- ORCID: 0000-0002-5478-2701 AD - Service of Endocrinology and Nutrition, University Clinical Hospital of Salamanca, Paseo de San Vicente No. 58, 37007 Salamanca, Spain. AD - Department of Medicine, University of Salamanca, Campus Miguel de Unamuno, s/n, 37007 Salamanca, Spain. FAU - Villanueva-Alvarado, H S AU - Villanueva-Alvarado HS AD - Service of Endocrinology and Nutrition, University Clinical Hospital of Salamanca, Paseo de San Vicente No. 58, 37007 Salamanca, Spain. FAU - Corrales-Hernandez, J J AU - Corrales-Hernandez JJ AUID- ORCID: 0000-0002-9160-3880 AD - Service of Endocrinology and Nutrition, University Clinical Hospital of Salamanca, Paseo de San Vicente No. 58, 37007 Salamanca, Spain. AD - Department of Medicine, University of Salamanca, Campus Miguel de Unamuno, s/n, 37007 Salamanca, Spain. AD - Cancer Research Institute (IBMCC-CSIC/USAL) and Institute for Biomedical Research, University of Salamanca, Salamanca, Spain. FAU - Higueruela-Minguez, C AU - Higueruela-Minguez C AD - Service of Endocrinology and Nutrition, University Clinical Hospital of Salamanca, Paseo de San Vicente No. 58, 37007 Salamanca, Spain. FAU - Feito-Perez, J AU - Feito-Perez J AD - Service of Anatomic Pathology, University Clinical Hospital of Salamanca, Paseo de San Vicente No. 58, 37007 Salamanca, Spain. FAU - Recio-Cordova, J M AU - Recio-Cordova JM AD - Service of Endocrinology and Nutrition, University Clinical Hospital of Salamanca, Paseo de San Vicente No. 58, 37007 Salamanca, Spain. AD - Department of Medicine, University of Salamanca, Campus Miguel de Unamuno, s/n, 37007 Salamanca, Spain. LA - eng PT - Case Reports DEP - 20171101 PL - United States TA - Case Rep Endocrinol JT - Case reports in endocrinology JID - 101576457 PMC - PMC5687133 EDAT- 2017/12/12 06:00 MHDA- 2017/12/12 06:01 PMCR- 2017/11/01 CRDT- 2017/12/12 06:00 PHST- 2017/06/29 00:00 [received] PHST- 2017/10/10 00:00 [accepted] PHST- 2017/12/12 06:00 [entrez] PHST- 2017/12/12 06:00 [pubmed] PHST- 2017/12/12 06:01 [medline] PHST- 2017/11/01 00:00 [pmc-release] AID - 10.1155/2017/2390797 [doi] PST - ppublish SO - Case Rep Endocrinol. 2017;2017:2390797. doi: 10.1155/2017/2390797. Epub 2017 Nov 1.