PMID- 29226357
OWN - NLM
STAT- MEDLINE
DCOM- 20181023
LR  - 20181023
IS  - 1540-8175 (Electronic)
IS  - 0742-2822 (Linking)
VI  - 35
IP  - 2
DP  - 2018 Feb
TI  - Atrial deformation correlated with functional capacity in mitral stenosis 
      patients.
PG  - 190-195
LID - 10.1111/echo.13770 [doi]
AB  - BACKGROUND: Left atrial (LA) dysfunction, expressed as impaired LA deformation 
      using two-dimensional (2D) strain imaging, has been observed in association with 
      rheumatic mitral stenosis (MS). However, the clinical role of speckle tracking 
      echocardiography (STE)-derived LA strain has rarely been studied in MS. AIM: This 
      study aimed to identify the determinants of New York Heart Association (NYHA) 
      functional class in patients with mitral stenosis and to investigate the 
      relationship between left atrial deformation as measured by two-dimensional 
      STE-derived LA strain and heart failure symptoms. METHODS: Sixty-nine consecutive 
      patients (20 males and 49 females; mean age: 61 +/- 14 years) with rheumatic MS 
      were evaluated using comprehensive 2D and color Doppler echocardiography 
      including STE-derived LA strain (LAS) and peak positive filling strain rate 
      (LASRr) during the LA reservoir phase. Those results were then correlated with 
      NYHA functional class. RESULTS: There were 15 (22%) patients in functional class 
      I, 42 (61%) in functional class II, and 12 (17%) in functional class III. There 
      were no significant differences in mitral valve area, pressure gradient, 
      pulmonary artery pressure, LA emptying fraction, or left ventricular ejection 
      fraction between functional classes. Upon multivariate analysis (controlling for 
      diuretics usage), LAS (ss = -0.233, P = .045) and LASRr (ss = -0.277, P = .014) 
      were independent factors in determining NYHA functional class. CONCLUSIONS: In 
      stable patients with MS, NYHA functional class independently correlated with LAS 
      and LASRr. Left atrial (LA) deformation correlated with heart failure symptoms in 
      patients with MS.
CI  - (c) 2017, Wiley Periodicals, Inc.
FAU - Chien, Chen-Yu
AU  - Chien CY
AD  - Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical 
      Foundation, Chiayi, Taiwan.
FAU - Chen, Chih-Wei
AU  - Chen CW
AD  - Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical 
      Foundation, Chiayi, Taiwan.
AD  - School of Medicine, Tzu Chi University, Hualien, Taiwan.
FAU - Lin, Tin-Kwang
AU  - Lin TK
AD  - Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical 
      Foundation, Chiayi, Taiwan.
AD  - School of Medicine, Tzu Chi University, Hualien, Taiwan.
FAU - Lin, Yu
AU  - Lin Y
AD  - Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical 
      Foundation, Chiayi, Taiwan.
FAU - Lin, Jnnu-Wen
AU  - Lin JW
AD  - Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical 
      Foundation, Chiayi, Taiwan.
FAU - Li, Yi-Da
AU  - Li YD
AD  - Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical 
      Foundation, Chiayi, Taiwan.
AD  - School of Medicine, Tzu Chi University, Hualien, Taiwan.
FAU - Chen, Chi-Hsien
AU  - Chen CH
AD  - Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical 
      Foundation, Chiayi, Taiwan.
FAU - Tsai, Wei-Chuan
AU  - Tsai WC
AUID- ORCID: 0000-0001-9328-4863
AD  - Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, 
      Taiwan.
LA  - eng
PT  - Journal Article
DEP - 20171211
PL  - United States
TA  - Echocardiography
JT  - Echocardiography (Mount Kisco, N.Y.)
JID - 8511187
SB  - IM
MH  - Aged
MH  - Atrial Function, Left
MH  - Echocardiography/*methods
MH  - Echocardiography, Doppler, Color
MH  - Female
MH  - Heart Atria/diagnostic imaging/physiopathology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Stenosis/*diagnostic imaging/*physiopathology
MH  - Retrospective Studies
OTO - NOTNLM
OT  - NYHA functional class
OT  - atrial deformation
OT  - mitral stenosis
OT  - speckle tracking echocardiography-derived LA strain
EDAT- 2017/12/12 06:00
MHDA- 2018/10/24 06:00
CRDT- 2017/12/12 06:00
PHST- 2017/12/12 06:00 [pubmed]
PHST- 2018/10/24 06:00 [medline]
PHST- 2017/12/12 06:00 [entrez]
AID - 10.1111/echo.13770 [doi]
PST - ppublish
SO  - Echocardiography. 2018 Feb;35(2):190-195. doi: 10.1111/echo.13770. Epub 2017 Dec 
      11.