PMID- 29228774
OWN - NLM
STAT- MEDLINE
DCOM- 20180613
LR  - 20180613
IS  - 1520-5827 (Electronic)
IS  - 0743-7463 (Linking)
VI  - 34
IP  - 2
DP  - 2018 Jan 16
TI  - Supramolecular Hydrogel Derived from a C(3)-Symmetric Boronic Acid Derivative for 
      Stimuli-Responsive Release of Insulin and Doxorubicin.
PG  - 685-692
LID - 10.1021/acs.langmuir.7b03326 [doi]
AB  - A C(3)-symmetric triazine based triboronic acid (HG1) was designed and 
      synthesized. HG1 was found to give hydrogel in DMSO-water (1:9). The hydrogel was 
      rheo-reversible and thermoreversible over a few cycles. Single-crystal X-ray 
      diffraction (SXRD) studies on the crystals of HG1 established the presence of 
      honeycomb network in which solvent molecules (DMSO and water) were occluded. SXRD 
      data corroborated well with the hypothesis based on which HG1 was designed. 
      Stimuli responsive release (in vitro) of insulin and doxorubicin from the 
      hydrogel was also achieved.
FAU - Sarkar, Koushik
AU  - Sarkar K
AD  - Department of Organic Chemistry, Indian Association for the Cultivation of 
      Science , 2A & 2B Raja S. C. Mullick Road, Kolkata 700032, India.
FAU - Dastidar, Parthasarathi
AU  - Dastidar P
AUID- ORCID: 0000-0002-1011-2386
AD  - Department of Organic Chemistry, Indian Association for the Cultivation of 
      Science , 2A & 2B Raja S. C. Mullick Road, Kolkata 700032, India.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20171227
PL  - United States
TA  - Langmuir
JT  - Langmuir : the ACS journal of surfaces and colloids
JID - 9882736
RN  - 0 (Boronic Acids)
RN  - 0 (Drug Carriers)
RN  - 0 (Hydrogels)
RN  - 0 (Insulin)
RN  - 0 (Macromolecular Substances)
RN  - 0 (Triazines)
RN  - 80168379AG (Doxorubicin)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
EIN - Langmuir. 2018 Jul 24;34(29):8708. PMID: 30009607
MH  - Animals
MH  - Boronic Acids/chemical synthesis/*chemistry/metabolism
MH  - Doxorubicin/*chemistry
MH  - Drug Carriers/chemical synthesis/*chemistry/metabolism
MH  - Drug Liberation
MH  - Glucose/chemistry
MH  - Hydrogels/chemical synthesis/*chemistry/metabolism
MH  - Hydrogen Bonding
MH  - Hydrogen-Ion Concentration
MH  - Insulin/*chemistry
MH  - Macromolecular Substances/chemical synthesis/chemistry/metabolism
MH  - Mice
MH  - Microscopy, Fluorescence
MH  - Porosity
MH  - RAW 264.7 Cells
MH  - Rheology
MH  - Triazines/chemical synthesis/*chemistry/metabolism
EDAT- 2017/12/13 06:00
MHDA- 2018/06/14 06:00
CRDT- 2017/12/13 06:00
PHST- 2017/12/13 06:00 [pubmed]
PHST- 2018/06/14 06:00 [medline]
PHST- 2017/12/13 06:00 [entrez]
AID - 10.1021/acs.langmuir.7b03326 [doi]
PST - ppublish
SO  - Langmuir. 2018 Jan 16;34(2):685-692. doi: 10.1021/acs.langmuir.7b03326. Epub 2017 
      Dec 27.