PMID- 29231566 OWN - NLM STAT- MEDLINE DCOM- 20180618 LR - 20181202 IS - 0255-2930 (Print) IS - 0255-2930 (Linking) VI - 36 IP - 8 DP - 2016 Aug 12 TI - [Effect of moxibustion combined with autohemotherapy of acupoint injection for life quality of allergic rhinitis with qi deficiency of lung and spleen:a randomized controlled trial]. PG - 815-819 LID - 10.13703/j.0255-2930.2016.08.010 [doi] AB - OBJECTIVE: To observe the effects of moxibustion combined with autohemotherapy of acupoint injection and simple moxibustion for allergic rhinitis(AR) with qi deficiency of lung and spleen and to explore its mechanism. METHODS: By random number table,75 patients who matched the criteria were assigned into a moxibustion combined with autohemotherapy of acupoint injection group(a combination group,37 cases) and a moxibustion group(38 cases). In the combination group,moxibustion was used at bilateral Yingxiang(LI 20) and injection bila-teral Feishu(BL 13),Pishu(BL 20) and Zusanli(ST 36). In the moxibustion group,moxibustion was applied bilaterally at all the above acupoints. Acupoint injection was given twice a week,and moxibustion once a day,seven days as a course. The patients were observed for four courses and followed up half a year after treatment. Rhinoconjunctivitis quality of life questionnaire(RQLQ) was compared before and after treatment and at follow-up. The short-term and long-term effects as well as the changes of interferon-gamma(IFN-gamma),interleukin-4(IL-4) and immunoglobulin E(IgE) were observed in the two group. RESULTS: After treatment,the obviously effective rate of the combination group was 75.68%(28/37),which was higher than 52.63%(20/38) of the moxibustion group(P<0.05). But at follow-up, the obviously effective rate of the moxibustion group was 47.37%(18/38),which was better than 24.32%(9/37) of the combination group(P<0.05). Life quality of the two group in all aspects after treatment and at follow-up were apparently improved compared with the baseline(P<0.01,P<0.05). After treatment,the life quality,sleep condition,non nasal-eye symptoms,behavior issue of the combination group were superior to those of the moxibustion group(all P<0.05),and at follow-up,the above outcomes,the eye and nasal symptoms as well as emotional response of the mo-xibustion group were better(all P<0.05). There was statistical significance in the two group about serum IFN-gamma,IgE,IL-4 before and after treatment(P<0.01,P<0.05),and significance existed between the two groups(P<0.05). CONCLUSIONS: Moxibustion combined with autohemotherapy of acupoint injection can effectively improve the short-term quality of life of AR with qi deficiency of lung and spleen. The mechanism may be related to balancing the immune response of Th1 and Th2. FAU - Hu, Rong AU - Hu R AD - Hunan Traditional Chinese Medical College, Zhuzhou 412012, China. FAU - Tang, Sen AU - Tang S AD - The First Affiliated Hospital of Hunan Traditional Chinese Medical College. FAU - Liu, Huai AU - Liu H AD - Hunan Traditional Chinese Medical College, Zhuzhou 412012, China. FAU - Li, Zaiyun AU - Li Z AD - The First Affiliated Hospital of Hunan Traditional Chinese Medical College. FAU - Lou, Tianxiao AU - Lou T AD - Hunan Traditional Chinese Medical College, Zhuzhou 412012, China. FAU - He, Shuguang AU - He S AD - The First Affiliated Hospital of Hunan Traditional Chinese Medical College. LA - chi PT - Journal Article PT - Randomized Controlled Trial PL - China TA - Zhongguo Zhen Jiu JT - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JID - 8600658 SB - IM MH - *Acupuncture Points MH - *Blood Transfusion, Autologous MH - Humans MH - Lung MH - Moxibustion/*methods MH - *Qi MH - *Quality of Life MH - Rhinitis, Allergic/*therapy MH - Spleen OTO - NOTNLM OT - acupoint injection OT - allergic rhinitis OT - autohemotherapy OT - interferon-gamma(IFN-gamma) OT - interleukin-4(IL-4) OT - moxibustion OT - quality of life OT - randomized controlled trial (RCT) EDAT- 2016/08/12 00:00 MHDA- 2018/06/19 06:00 CRDT- 2017/12/13 06:00 PHST- 2017/12/13 06:00 [entrez] PHST- 2016/08/12 00:00 [pubmed] PHST- 2018/06/19 06:00 [medline] AID - 10.13703/j.0255-2930.2016.08.010 [doi] PST - ppublish SO - Zhongguo Zhen Jiu. 2016 Aug 12;36(8):815-819. doi: 10.13703/j.0255-2930.2016.08.010.