PMID- 29238020
OWN - NLM
STAT- MEDLINE
DCOM- 20180112
LR  - 20180112
IS  - 1349-7413 (Electronic)
IS  - 0911-4300 (Linking)
VI  - 40
IP  - 5
DP  - 2017
TI  - [Prolonged optic disc swelling in Kawasaki disease - A case report and literature 
      review].
PG  - 377-381
LID - 10.2177/jsci.40.377 [doi]
AB  -   Kawasaki disease (KD), an acute childhood panvasculitis, presents a variety of 
      ocular complications as well as conjunctival injection among the principal 
      symptoms. However, most pediatricians are unfamiliar with the ophthalmological 
      complications of KD. A 2-year-old girl was referred to us from the ophthalmology 
      department due to injected bulbar conjunctivae and optic disc swelling. She had 
      familial exudative vitreoretinopathy as an underlying disease and the ocular 
      findings had been made by chance while the patient was receiving an eye 
      examination. Although she was afebrile at the time of her first medical 
      interview, KD was diagnosed based on the presence of four of the principal 
      symptoms including fever and dilatation of the coronary arteries. Intravenous 
      immunoglobulin (IVIG) therapy was administered on Day 15 from the onset of fever. 
      After IVIG administration, her laboratory test results showed rapid improvement 
      but her optic disc swelling continued for six months. Eye complications in KD 
      generally occur in the anterior segment, and recovery occurs within two months. 
      Past reports have shown that in three of seven KD cases with optic disc 
      involvement, optic disc swelling lasted over two months. This is the second case 
      in which the condition lasted six months.
FAU - Tsumura, Yusuke
AU  - Tsumura Y
AD  - National Center for Child Health and Development, Department of Postgraduate 
      Education and Training.
FAU - Masuda, Hiroshi
AU  - Masuda H
AD  - National Center for Child Health and Development, Department of General 
      Pediatrics and Interdisciplinary Medicine.
FAU - Nishina, Sachiko
AU  - Nishina S
AD  - National Center for Child Health and Development, Division of Ophthalmology and 
      Laboratory for Visual Science.
FAU - Kobayashi, Tohru
AU  - Kobayashi T
AD  - National Center for Child Health and Development, Division of Clinical Research 
      Planning, Department of Development Strategy, Center for Clinical Research and 
      Development.
FAU - Ono, Hiroshi
AU  - Ono H
AD  - National Center for Child Health and Development, Division of Cardiology.
FAU - Kato, Hitoshi
AU  - Kato H
AD  - National Center for Child Health and Development, Division of Cardiology.
FAU - Abe, Jun
AU  - Abe J
AD  - National Center for Child Health and Development, Division of Advanced Medicine 
      for Virus Infections, National Research Institute for Child Health and 
      Development.
FAU - Ishiguro, Akira
AU  - Ishiguro A
AD  - National Center for Child Health and Development, Department of Postgraduate 
      Education and Training.
LA  - jpn
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Nihon Rinsho Meneki Gakkai Kaishi
JT  - Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology
JID - 9505992
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Child, Preschool
MH  - Conjunctiva/pathology
MH  - Female
MH  - Humans
MH  - Immunoglobulins, Intravenous/administration & dosage
MH  - Incidental Findings
MH  - Mucocutaneous Lymph Node Syndrome/*complications/therapy
MH  - Optic Disk/*pathology
MH  - Optic Nerve Diseases/*etiology/*pathology
MH  - Time Factors
MH  - Treatment Outcome
MH  - Vitreoretinopathy, Proliferative/complications/genetics
OTO - NOTNLM
OT  - Kawasaki disease
OT  - complication
OT  - eye involvement
OT  - optic disc swelling
EDAT- 2017/12/15 06:00
MHDA- 2018/01/13 06:00
CRDT- 2017/12/15 06:00
PHST- 2017/12/15 06:00 [entrez]
PHST- 2017/12/15 06:00 [pubmed]
PHST- 2018/01/13 06:00 [medline]
AID - 10.2177/jsci.40.377 [doi]
PST - ppublish
SO  - Nihon Rinsho Meneki Gakkai Kaishi. 2017;40(5):377-381. doi: 10.2177/jsci.40.377.