PMID- 29239727 OWN - NLM STAT- MEDLINE DCOM- 20181031 LR - 20181031 IS - 1879-1476 (Electronic) IS - 0385-8146 (Linking) VI - 45 IP - 4 DP - 2018 Aug TI - Clinical effects of submucosal middle turbinectomy for eosinophilic chronic rhinosinusitis. PG - 765-771 LID - S0385-8146(17)30212-2 [pii] LID - 10.1016/j.anl.2017.11.013 [doi] AB - OBJECTIVE: The preservation or resection of the middle turbinate (MT) during endoscopic sinus surgery (ESS) currently remains a matter of debate. The present study aimed to investigate the effects of submucosal middle turbinectomy (SMT) in ESS for eosinophilic chronic rhinosinusitis (ECRS). METHODS: The study included 38 ECRS patients (63 sides) who had undergone full-house ESS with SMT and 20 ECRS patients (40 sides) without SMT as a control group. Post-operative middle turbinate lateralization (MTL), synechia formation, and the patency grade of the olfactory cleft (OC) were assessed as the primary outcomes 3 months after surgery. CT scans and the T&T test were performed on the SMT group 3 months after surgery and assessed as secondary outcomes. RESULTS: MTL and synechia formation rates were slightly higher in the control group than in the SMT group (20% vs. 7.9%, p=0.072, 17.5% vs. 9.5%, p=0.235), although neither reached statistically significance. The mean patency score of OC was significantly better in the SMT group than in the control group (0.5+/-0.6 vs. 1.3+/-0.7, <0.001). CT findings and T&T test scores showed good improvements after SMT combined with ESS. No major adverse events occurred due to SMT. CONCLUSION: We demonstrated the potential advantages of SMT for ECRS patients. This method may avoid physiological functional loss through its preservation of the mucosa and structure of the MT. CI - Copyright (c) 2017 Elsevier B.V. All rights reserved. FAU - Akiyama, Kosuke AU - Akiyama K AD - Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan. Electronic address: kakaka@med.kagawa-u.ac.jp. FAU - Samukawa, Yasushi AU - Samukawa Y AD - Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan. FAU - Takahashi, Satoshi AU - Takahashi S AD - Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan. FAU - Ouchi, Youhei AU - Ouchi Y AD - Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan. FAU - Hoshikawa, Hiroshi AU - Hoshikawa H AD - Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kita-gun, Miki-cho, Ikenobe 1750-1, Kagawa 761-0793, Japan. LA - eng PT - Journal Article DEP - 20171126 PL - Netherlands TA - Auris Nasus Larynx JT - Auris, nasus, larynx JID - 7708170 SB - IM MH - Adult MH - Aged MH - Chronic Disease MH - Endoscopy MH - Eosinophilia/*surgery MH - Female MH - Humans MH - Male MH - Middle Aged MH - Nasal Septum/diagnostic imaging MH - Nasal Surgical Procedures/*methods MH - Natural Orifice Endoscopic Surgery MH - Otorhinolaryngologic Surgical Procedures/methods MH - Postoperative Complications/diagnostic imaging/*epidemiology MH - Prospective Studies MH - Rhinitis/*surgery MH - Sinusitis/*surgery MH - Tissue Adhesions/diagnostic imaging/epidemiology MH - Tomography, X-Ray Computed MH - Treatment Outcome MH - Turbinates/diagnostic imaging/*surgery OTO - NOTNLM OT - Endoscopic sinus surgery OT - Eosinophilic chronic rhinosinusitis OT - Lateralization OT - Middle turbinate OT - Synechia formation EDAT- 2017/12/15 06:00 MHDA- 2018/11/01 06:00 CRDT- 2017/12/15 06:00 PHST- 2017/03/01 00:00 [received] PHST- 2017/10/02 00:00 [revised] PHST- 2017/11/14 00:00 [accepted] PHST- 2017/12/15 06:00 [pubmed] PHST- 2018/11/01 06:00 [medline] PHST- 2017/12/15 06:00 [entrez] AID - S0385-8146(17)30212-2 [pii] AID - 10.1016/j.anl.2017.11.013 [doi] PST - ppublish SO - Auris Nasus Larynx. 2018 Aug;45(4):765-771. doi: 10.1016/j.anl.2017.11.013. Epub 2017 Nov 26.