PMID- 29241238 OWN - NLM STAT- MEDLINE DCOM- 20180201 LR - 20200225 IS - 1833-3516 (Print) IS - 2209-1491 (Electronic) IS - 1833-3516 (Linking) VI - 47 IP - 4 DP - 2017 Dec TI - Hyperbaric oxygen-associated seizure leading to stroke. PG - 260-262 LID - 10.28920/dhm47.4.260-262 [doi] AB - Oxygen toxicity seizures are a well-known complication of hyperbaric oxygen treatment (HBOT). Until now, there have not been any reported cases of an acute ischaemic event (stroke) as the result of a HBOT-associated oxygen toxicity seizure. We report an event in which a seizure and stroke occurred together and consider that the stroke may have been caused by seizure-induced demand ischaemia. This challenges the generally held view that oxygen toxicity seizures in the clinical hyperbaric setting are benign. A discussion of the literature on the subject of seizure-induced brain injury is included. Risk factors for cerebrovascular disease should be taken into consideration in determining treatment pressures for HBOT, as reducing pressure reduces seizure risk. CI - Copyright: This article is the copyright of the authors who grant Diving and Hyperbaric Medicine a non-exclusive licence to publish the article in printed and other forms. FAU - Warchol, Jordan M AU - Warchol JM AD - Department of Emergency Medicine, 981150 NMC, University of Nebraska Medical Centre, Omaha, NE 68198-1150, USA, jeffrey.cooper@unmc.edu. FAU - Cooper, Jeffrey S AU - Cooper JS AD - Department of Emergency Medicine, University of Nebraska Medical Centre, Omaha, Nebraska, USA. FAU - Diesing, Thomas S AU - Diesing TS AD - Department of Neurology, University of Nebraska Medical Centre, Omaha. LA - eng PT - Case Reports PL - Australia TA - Diving Hyperb Med JT - Diving and hyperbaric medicine JID - 101282742 SB - IM MH - Aged, 80 and over MH - Humans MH - Hyperbaric Oxygenation/*adverse effects MH - Leg Ulcer/therapy MH - Male MH - Neurologic Examination MH - Risk Factors MH - Seizures/*etiology MH - Stroke/*etiology PMC - PMC6706335 OTO - NOTNLM OT - Case reports OT - Central nervous system OT - Hyperoxia OT - Toxicity COIS- Conflict of interest and funding: nil EDAT- 2017/12/15 06:00 MHDA- 2018/02/02 06:00 PMCR- 2018/12/31 CRDT- 2017/12/15 06:00 PHST- 2017/09/07 00:00 [received] PHST- 2017/09/14 00:00 [accepted] PHST- 2017/12/15 06:00 [entrez] PHST- 2017/12/15 06:00 [pubmed] PHST- 2018/02/02 06:00 [medline] PHST- 2018/12/31 00:00 [pmc-release] AID - 10.28920/dhm47.4.260-262 [doi] PST - ppublish SO - Diving Hyperb Med. 2017 Dec;47(4):260-262. doi: 10.28920/dhm47.4.260-262.