PMID- 29250219
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1941-6911 (Print)
IS  - 1941-6911 (Electronic)
IS  - 1941-6911 (Linking)
VI  - 10
IP  - 1
DP  - 2017 Jun-Jul
TI  - Use of acoustic cardiography immediately following electrical cardioversion to 
      predict relapse of atrial fibrillation.
PG  - 1527
LID - 10.4022/jafib.1527 [doi]
LID - 1527
AB  - Predicting atrial fibrillation (AF) recurrence after successful electrical 
      cardioversion (ECV) is difficult. The main aim of this study was to investigate 
      whether acoustic cardiography (AUDICOR(R) 200) immediately post-ECV might provide 
      indices for AF relapse following cardioversion. Acoustic cardiography parameters 
      included Electromechanical Activation Time (EMAT), Left Ventricular Systolic Time 
      (LVST), QRS duration, heart rate and third heart sound intensity (S3 Strength). 
      We analysed data from 140 patients who underwent successful cardioversion and in 
      whom AUDICOR results and echocardiographic measurements immediately after 
      (baseline) ECV were available. Patients were prospectively followed-up at 4-6 
      weeks, 3 and 12 months post-ECV, and sinus rhythm maintenance was evaluated using 
      acoustic cardiography and Holter electrocardiography. The effect of each baseline 
      AUDICOR parameter on the hazard of AF relapse was investigated using Cox 
      proportional hazards (PH) models. Fifty patients (35.7%) had AF relapse. Of all 
      the AUDICOR parameters, only S3 Strength exhibited consistent predictive value. 
      Increasing S3 Strength increased the hazard of relapse in a univariable Cox PH 
      model (HR=2.52, p=0.003), and in two multivariable Cox PH model constructions 
      (Model 1 excluded heart rate and Model II excluded EMAT/RR, LVST and LVST/RR) 
      both of which included the parameters as continuous variables (Model I: HR=1.15, 
      p=0.042; Model II: HR=1.14, p=0.045) or the parameters dichotomized according to 
      suggested cut-points (Model I: HR=2.5, p=0.007; Model II: HR=2.09, p=0.031). In 
      conclusion, this study suggests that acoustic cardiography may be a simple 
      inexpensive and quantitative bedside method to assist in prediction of AF 
      recurrence after ECV.
FAU - Erne, Paul
AU  - Erne P
AD  - Laboratory of Signal Transduction, Department of Biomedicine, Basel University 
      Hospital and Basel University, Basel, Switzerland.
FAU - Resink, Therese J
AU  - Resink TJ
AD  - Department of Cardiology, Luzerner Kantonsspital, Luzern, Switzerland.
FAU - Mueller, Andrea
AU  - Mueller A
AD  - Department of Cardiology, Luzerner Kantonsspital, Luzern, Switzerland.
FAU - Coslovsky, Michael
AU  - Coslovsky M
AD  - Clinical Trial Unit, Basel University Hospital, Basel Switzerland.
FAU - Kobza, Richard
AU  - Kobza R
AD  - Department of Cardiology, Luzerner Kantonsspital, Luzern, Switzerland.
FAU - Conen, David
AU  - Conen D
AD  - Department of Cardiology, Basel University Hospital, Basel, Switzerland.
AD  - Population Health Research Institute, McMaster University, Hamilton, Canada.
FAU - Bauer, Peter
AU  - Bauer P
AD  - Inovise Medical, Inc., Beaverton, Oregon, USA.
FAU - Arand, Patricia
AU  - Arand P
AD  - Inovise Medical, Inc., Beaverton, Oregon, USA.
LA  - eng
PT  - Journal Article
DEP - 20170630
PL  - United States
TA  - J Atr Fibrillation
JT  - Journal of atrial fibrillation
JID - 101514767
PMC - PMC5673325
OTO - NOTNLM
OT  - Acoustic cardiography
OT  - Atrial fibrillation
OT  - Electrical cardioversion
OT  - Relapse
EDAT- 2017/12/19 06:00
MHDA- 2017/12/19 06:01
PMCR- 2017/06/30
CRDT- 2017/12/19 06:00
PHST- 2017/01/06 00:00 [received]
PHST- 2017/02/19 00:00 [revised]
PHST- 2017/05/14 00:00 [accepted]
PHST- 2017/12/19 06:00 [entrez]
PHST- 2017/12/19 06:00 [pubmed]
PHST- 2017/12/19 06:01 [medline]
PHST- 2017/06/30 00:00 [pmc-release]
AID - 10.4022/jafib.1527 [doi]
PST - epublish
SO  - J Atr Fibrillation. 2017 Jun 30;10(1):1527. doi: 10.4022/jafib.1527. eCollection 
      2017 Jun-Jul.