PMID- 29250648
OWN - NLM
STAT- MEDLINE
DCOM- 20180807
LR  - 20220409
IS  - 2066-8279 (Electronic)
IS  - 1220-0522 (Linking)
VI  - 58
IP  - 3
DP  - 2017
TI  - Cytological, histopathological and immunological aspects of autoimmune 
      thyroiditis: a review.
PG  - 731-738
AB  - Autoimmune thyroiditis (AT) is a disease that may be associated with many other 
      autoimmune endocrine and non-endocrine disorders. This disease is mediated by 
      both humoral and cellular mechanisms and it is the result of combined effects of 
      human leukocyte antigen (HLA) class II genes and non-HLA genes polymorphisms. The 
      clinical course of AT is variable and may be characterized by spontaneous 
      remission and by irreversible thyroid insufficiency as the consequence of 
      atrophic and fibrous transformation of the thyroid gland in other cases. In this 
      paper, the AT's etiology and immunological mechanism along with its cytological 
      and histopathological features are reviewed in order to increase our 
      understanding about the mechanism involved in pathogenesis of this disease and to 
      open new directions of investigations that will be useful in a better clinical 
      practice.
FAU - Buzduga, Catalin Mihai
AU  - Buzduga CM
AD  - Department of Ophthalmology, "Grigore T. Popa" University of Medicine and 
      Pharmacy, Iasi, Romania; costea10@yahoo.com; Department of Anatomy, Faculty of 
      Dental Medicine, "Ovidius" University, Constanta, Romania; esapte@ymail.com.
FAU - Costea, Claudia Florida
AU  - Costea CF
FAU - Dumitrescu, Gabriela FlorenTa
AU  - Dumitrescu GF
FAU - Turliuc, Mihaela Dana
AU  - Turliuc MD
FAU - Bogdanici, Camelia Margareta
AU  - Bogdanici CM
FAU - Cucu, Andrei
AU  - Cucu A
FAU - Dumitrescu, Nicoleta
AU  - Dumitrescu N
FAU - Indrei, Lucia
AU  - Indrei L
FAU - Sapte, Elena
AU  - Sapte E
FAU - Ciobanu Apostol, Delia Gabriela
AU  - Ciobanu Apostol DG
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Romania
TA  - Rom J Morphol Embryol
JT  - Romanian journal of morphology and embryology = Revue roumaine de morphologie et 
      embryologie
JID - 9112454
SB  - IM
MH  - Humans
MH  - Thyroid Gland/*pathology
MH  - Thyroiditis, Autoimmune/*immunology/*pathology
EDAT- 2017/12/19 06:00
MHDA- 2018/08/08 06:00
CRDT- 2017/12/19 06:00
PHST- 2017/12/19 06:00 [entrez]
PHST- 2017/12/19 06:00 [pubmed]
PHST- 2018/08/08 06:00 [medline]
AID - 580317731738 [pii]
PST - ppublish
SO  - Rom J Morphol Embryol. 2017;58(3):731-738.