PMID- 29256089 OWN - NLM STAT- MEDLINE DCOM- 20191111 LR - 20191111 IS - 1525-1497 (Electronic) IS - 0884-8734 (Print) IS - 0884-8734 (Linking) VI - 33 IP - 4 DP - 2018 Apr TI - Diabetes Mellitus Management Among Patients with Limited English Proficiency: A Systematic Review and Meta-Analysis. PG - 524-532 LID - 10.1007/s11606-017-4237-1 [doi] AB - BACKGROUND: Patients with limited English proficiency (LEP) and type 2 diabetes mellitus (T2DM) have several health disparities, including suboptimal patient-provider interactions, poorer glycemic control, and T2DM complications. Understanding existing interventions for improving T2DM outcomes in this population is critical for reducing disparities. METHODS: We performed a systematic review of randomized controlled trials (RCTs) and observational studies examining the effectiveness of interventions in improving T2DM outcomes among patients with LEP in North America. Quality was assessed using the Cochrane risk of bias tool for RCTs and the Newcastle-Ottawa Scale for non-RCT studies. Meta-analysis was conducted using the random-effects model. RESULTS: Fifty-four studies, 39 of which reported sufficient data for meta-analysis of glycemic control, were included. The interventions were associated with a statistically significant reduction in hemoglobin A(1c) (HbA(1c)) (weighted difference in means, -0.84% [95% CI, -0.97 to -0.71]) that was, however, very heterogeneous across studies (I(2) = 95.9%). Heterogeneity was explained by study design (lower efficacy in RCTs than non-RCTs) and by intervention length and delivery mode (greater reduction in interventions lasting <6 months or delivered face-to-face); P < 0.05 for all three covariates. The interventions were also associated in most studies with improvement in knowledge, self-efficacy in diabetes management, quality of life, blood pressure, and low-density lipoprotein cholesterol. DISCUSSION: Multiple types of interventions are available for T2DM management in patients with LEP. Multicomponent interventions delivered face-to-face seem most effective for glycemic control. More research is needed to better understand other aspects of multicomponent interventions that are critical for improving important outcomes among patients with T2DM and LEP. FAU - Njeru, Jane W AU - Njeru JW AD - Division of Primary Care Internal Medicine, Mayo Clinic, Rochester, MN, USA. njeru.jane@mayo.edu. FAU - Wieland, Mark L AU - Wieland ML AD - Division of Primary Care Internal Medicine, Mayo Clinic, Rochester, MN, USA. FAU - Kwete, Gracia AU - Kwete G AD - Mayo Clinic School of Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. AD - Massachusetts General Hospital, Boston, MA, USA. FAU - Tan, Eugene M AU - Tan EM AD - Division of Infectious Diseases, Mayo Clinic, Rochester, MN, USA. FAU - Breitkopf, Carmen Radecki AU - Breitkopf CR AD - Division of Health Care Policy and Research, Mayo Clinic, Rochester, MN, USA. FAU - Agunwamba, Amenah A AU - Agunwamba AA AD - Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA. FAU - Prokop, Larry J AU - Prokop LJ AD - Mayo Medical Library, Mayo Clinic, Rochester, MN, USA. FAU - Murad, M Hassan AU - Murad MH AD - Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA. AD - Division of Preventive, Occupational, and Aerospace Medicine, Mayo Clinic, Rochester, MN, USA. LA - eng PT - Journal Article PT - Meta-Analysis PT - Research Support, Non-U.S. Gov't PT - Systematic Review DEP - 20171218 PL - United States TA - J Gen Intern Med JT - Journal of general internal medicine JID - 8605834 SB - IM CIN - J Gen Intern Med. 2018 Jun;33(6):947. PMID: 29633126 MH - *Communication Barriers MH - Diabetes Mellitus, Type 2/*ethnology/*therapy MH - *Disease Management MH - Humans MH - Observational Studies as Topic/methods MH - Randomized Controlled Trials as Topic/methods MH - Self Care/*methods PMC - PMC5880756 OTO - NOTNLM OT - chronic disease OT - diabetes OT - disease management OT - health communication OT - language barriers OT - limited English proficiency COIS- The authors declare that they do not have a conflict of interest. EDAT- 2017/12/20 06:00 MHDA- 2019/11/12 06:00 PMCR- 2019/04/01 CRDT- 2017/12/20 06:00 PHST- 2017/03/06 00:00 [received] PHST- 2017/11/13 00:00 [accepted] PHST- 2017/06/14 00:00 [revised] PHST- 2017/12/20 06:00 [pubmed] PHST- 2019/11/12 06:00 [medline] PHST- 2017/12/20 06:00 [entrez] PHST- 2019/04/01 00:00 [pmc-release] AID - 10.1007/s11606-017-4237-1 [pii] AID - 4237 [pii] AID - 10.1007/s11606-017-4237-1 [doi] PST - ppublish SO - J Gen Intern Med. 2018 Apr;33(4):524-532. doi: 10.1007/s11606-017-4237-1. Epub 2017 Dec 18.