PMID- 29256458 OWN - NLM STAT- MEDLINE DCOM- 20180905 LR - 20180905 IS - 1998-3603 (Electronic) IS - 0970-9290 (Linking) VI - 28 IP - 6 DP - 2017 Nov-Dec TI - Topographic assessment of human enamel surface treated with different topical sodium fluoride agents: Scanning electron microscope consideration. PG - 617-622 LID - 10.4103/ijdr.IJDR_675_16 [doi] AB - INTRODUCTION: Continuous balanced demineralization and remineralization are natural dynamic processes in enamel. If the balance is interrupted and demineralization process dominates, it may eventually lead to the development of carious lesions in enamel and dentine. Fluoride helps control decay by enhancing remineralization and altering the structure of the tooth, making the surface less soluble. METHODOLOGY: One hundred and twenty sound human permanent incisors randomly and equally distributed into six groups as follows: Group I - Control, II - Sodium fluoride solution, III - Sodium fluoride gel, IV - Sodium fluoride varnish, V - Clinpro Tooth Creme (3M ESPE), and VI-GC Tooth Mousse Plus or MI Paste Plus. The samples were kept in artificial saliva for 12 months, and the topical fluoride agents were applied to the respective sample groups as per the manufacturer instructions. Scanning electron microscope (SEM) evaluation of all the samples after 6 and 12 months was made. RESULTS: Morphological changes on the enamel surface after application of fluoride in SEM revealed the presence of globular precipitate in all treated samples. Amorphous, globular, and crystalline structures were seen on the enamel surface of the treated samples. Clear differences were observed between the treated and untreated samples. CONCLUSION: Globular structures consisting of amorphous CaF2precipitates, which acted as a fluoride reservoir, were observed on the enamel surface after action of different sodium fluoride agents. CPP-ACPF (Tooth Mousse) and Tricalcium phosphate with fluoride (Clinpro tooth creme) are excellent delivery vehicles available in a slow release amorphous form to localize fluoride at the tooth surface. FAU - Brar, Gurlal Singh AU - Brar GS AD - Department of Pedodontics and Preventive Dentistry, Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India. FAU - Arora, Amandeep Singh AU - Arora AS AD - Department of Pedodontics and Preventive Dentistry, Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India. FAU - Khinda, Vineet Inder Singh AU - Khinda VIS AD - Department of Pedodontics and Preventive Dentistry, Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India. FAU - Kallar, Shiminder AU - Kallar S AD - Department of Pedodontics and Preventive Dentistry, Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India. FAU - Arora, Karuna AU - Arora K AD - Department of Orthodontics, Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India. LA - eng PT - Comparative Study PT - Journal Article PL - India TA - Indian J Dent Res JT - Indian journal of dental research : official publication of Indian Society for Dental Research JID - 9202990 RN - 8ZYQ1474W7 (Sodium Fluoride) MH - Administration, Topical MH - Dental Enamel/*drug effects/*ultrastructure MH - Humans MH - In Vitro Techniques MH - Microscopy, Electron, Scanning MH - Random Allocation MH - Sodium Fluoride/administration & dosage/*pharmacology MH - Surface Properties EDAT- 2017/12/20 06:00 MHDA- 2018/09/06 06:00 CRDT- 2017/12/20 06:00 PHST- 2017/12/20 06:00 [entrez] PHST- 2017/12/20 06:00 [pubmed] PHST- 2018/09/06 06:00 [medline] AID - IndianJDentRes_2017_28_6_617_221064 [pii] AID - 10.4103/ijdr.IJDR_675_16 [doi] PST - ppublish SO - Indian J Dent Res. 2017 Nov-Dec;28(6):617-622. doi: 10.4103/ijdr.IJDR_675_16.