PMID- 29260464
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 1568-5888 (Print)
IS  - 1876-6250 (Electronic)
IS  - 1568-5888 (Linking)
VI  - 26
IP  - 2
DP  - 2018 Feb
TI  - Veno-arterial extracorporeal membrane oxygenation in addition to primary PCI in 
      patients presenting with ST-elevation myocardial infarction.
PG  - 76-84
LID - 10.1007/s12471-017-1068-y [doi]
AB  - INTRODUCTION: Primary percutaneous coronary intervention (pPCI) in ST-elevation 
      myocardial infarction (STEMI) can cause great haemodynamic instability. 
      Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can provide 
      haemodynamic support in patients with STEMI but data on outcome and complications 
      are scarce. METHODS: An in-hospital registry was conducted enrolling all patients 
      receiving VA-ECMO. Patients were analysed for medical history, mortality, 
      neurological outcome, complications and coronary artery disease. RESULTS: Between 
      2011 and 2016, 12 patients underwent pPCI for STEMI and received VA-ECMO for 
      haemodynamic support. The majority of the patients were male (10/12) with 
      a median age of 63 (47-75) years and 4 of the 12 patients had a history of 
      coronary artery disease. A cardiac arrest was witnessed in 11 patients. The left 
      coronary artery was compromised in 8 patients and 4 had right coronary artery 
      disease. All patients were in Killip class IV. Survival to discharge was 67% 
      (8/12), 1‑year survival was 42% (5/12), 2 patients have not yet reached the 
      1‑year survival point but are still alive and 1 patient died within a year after 
      discharge. All-cause mortality was 42% (5/12) of which mortality on ECMO was 33% 
      (4/12). Patient-related complications occurred in 6 of the 12 patients: 1 patient 
      suffered major neurological impairment, 2 patients suffered haemorrhage at the 
      cannula site, 2 patients had limb ischaemia and 1 patient had a haemorrhage 
      elsewhere. There were no VA-ECMO hardware malfunctions. CONCLUSION: VA-ECMO in 
      pPCI for STEMI has a high survival rate and neurological outcome is good, even 
      when the patient is admitted with a cardiac arrest.
FAU - van den Brink, F S
AU  - van den Brink FS
AD  - Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands. 
      f.van.den.brink@antoniusziekenhuis.nl.
FAU - Magan, A D
AU  - Magan AD
AD  - Department of Intensive Care, St Antonius Hospital, Nieuwegein, The Netherlands.
FAU - Noordzij, P G
AU  - Noordzij PG
AD  - Department of Intensive Care, St Antonius Hospital, Nieuwegein, The Netherlands.
FAU - Zivelonghi, C
AU  - Zivelonghi C
AD  - Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.
FAU - Agostoni, P
AU  - Agostoni P
AD  - Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.
FAU - Eefting, F D
AU  - Eefting FD
AD  - Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.
FAU - Ten Berg, J M
AU  - Ten Berg JM
AD  - Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.
FAU - Suttorp, M J
AU  - Suttorp MJ
AD  - Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.
FAU - Rensing, B R
AU  - Rensing BR
AD  - Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.
FAU - van Kuijk, J P
AU  - van Kuijk JP
AD  - Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.
FAU - Klein, P
AU  - Klein P
AD  - Department of Cardio-Thoracic Surgery, St Antonius Hospital, Nieuwegein, The 
      Netherlands.
FAU - Scholten, E
AU  - Scholten E
AD  - Department of Intensive Care, St Antonius Hospital, Nieuwegein, The Netherlands.
FAU - van der Heyden, J A S
AU  - van der Heyden JAS
AD  - Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Neth Heart J
JT  - Netherlands heart journal : monthly journal of the Netherlands Society of 
      Cardiology and the Netherlands Heart Foundation
JID - 101095458
PMC - PMC5783893
OTO - NOTNLM
OT  - Cardiogenic Shock
OT  - Circulatory Support
OT  - ECMO
OT  - STEMI
COIS- F.S. van den Brink, A.D. Magan, P.G. Noordzij, C. Zivelonghi, P. Agostoni, 
      F.D. Eefting, J.M. ten Berg, M.J. Suttorp, B.R. Rensing, J.P. van Kuijk, P. Klein 
      and E. Scholten, J.A.S van der Heyden declare that they have no competing 
      interests.
EDAT- 2017/12/21 06:00
MHDA- 2017/12/21 06:01
PMCR- 2017/12/19
CRDT- 2017/12/21 06:00
PHST- 2017/12/21 06:00 [pubmed]
PHST- 2017/12/21 06:01 [medline]
PHST- 2017/12/21 06:00 [entrez]
PHST- 2017/12/19 00:00 [pmc-release]
AID - 10.1007/s12471-017-1068-y [pii]
AID - 1068 [pii]
AID - 10.1007/s12471-017-1068-y [doi]
PST - ppublish
SO  - Neth Heart J. 2018 Feb;26(2):76-84. doi: 10.1007/s12471-017-1068-y.