PMID- 29264042 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210109 IS - 2189-6577 (Print) IS - 2189-7948 (Electronic) IS - 2189-7948 (Linking) VI - 18 IP - 5 DP - 2017 Oct TI - Intractable otitis media as a diagnostic clue to antineutrophil cytoplasmic antibody-associated vasculitis. PG - 279-281 LID - 10.1002/jgf2.67 [doi] AB - Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) presents a variety of manifestations. Two patients with a history of intractable otitis media were diagnosed as having AAV. One was an 87-year-old woman who presented with cough, anorexia, and fever with a one-year and four-month history of otitis media, and the other was a 65-year-old woman with arthritis that appeared after the diagnosis of otitis media. The history of otitis media was a diagnostic clue to AAV in both patients. Diagnosis at the early localized stage is crucial to prevent irreversible status of AAV. Primary care physicians should be aware of the otological manifestation of AAV. FAU - Ishikawa, Yukiko AU - Ishikawa Y AD - Division of General Internal Medicine Jichi Medical University Hospital Shimotsuke Japan. FAU - Takeda, Koichi AU - Takeda K AD - Division of Rheumatology and Clinical Immunology Department of Medicine Jichi Medical University Shimotsuke Japan. FAU - Akiyama, Yoichiro AU - Akiyama Y AD - Division of Rheumatology and Clinical Immunology Department of Medicine Jichi Medical University Shimotsuke Japan. FAU - Matsumura, Masami AU - Matsumura M AD - Division of General Internal Medicine Jichi Medical University Hospital Shimotsuke Japan. LA - eng PT - Case Reports DEP - 20170413 PL - Japan TA - J Gen Fam Med JT - Journal of general and family medicine JID - 101689875 PMC - PMC5689439 OTO - NOTNLM OT - antineutrophil cytoplasmic antibody OT - otitis media OT - vasculitis EDAT- 2017/12/22 06:00 MHDA- 2017/12/22 06:01 PMCR- 2017/04/13 CRDT- 2017/12/22 06:00 PHST- 2016/06/13 00:00 [received] PHST- 2016/09/28 00:00 [accepted] PHST- 2017/12/22 06:00 [entrez] PHST- 2017/12/22 06:00 [pubmed] PHST- 2017/12/22 06:01 [medline] PHST- 2017/04/13 00:00 [pmc-release] AID - JGF267 [pii] AID - 10.1002/jgf2.67 [doi] PST - epublish SO - J Gen Fam Med. 2017 Apr 13;18(5):279-281. doi: 10.1002/jgf2.67. eCollection 2017 Oct.