PMID- 29269666
OWN - NLM
STAT- MEDLINE
DCOM- 20180827
LR  - 20181202
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Print)
IS  - 0918-2918 (Linking)
VI  - 57
IP  - 8
DP  - 2018 Apr 15
TI  - The Diagnosis of Gastric Mucosa-associated Lymphoid Tissue Lymphoma by Flow 
      Cytometry and Fluorescence in situ Hybridization of Biopsy Specimens.
PG  - 1081-1086
LID - 10.2169/internalmedicine.9617-17 [doi]
AB  - Mucosa-associated lymphoid tissue (MALT) lymphoma and reactive inflammatory 
      lymphoid changes are frequently difficult to distinguish based on a routine 
      histological differential diagnosis. We were unable to diagnose gastric MALT 
      lymphoma histologically using specimens obtained by endoscopy, although a flow 
      cytometry (FCM) analysis demonstrated clonality of neoplastic cells by separating 
      cells by CD45 gating. Furthermore, a fluorescence in situ hybridization (FISH) 
      analysis showed trisomy 18. We therefore diagnosed gastric MALT lymphoma with 
      trisomy 18. We recommend that FCM and FISH analyses of biopsy specimens be 
      considered for diagnosing gastric MALT lymphoma if this diagnosis is suspected 
      based on endoscopic findings.
FAU - Matsueda, Katsunori
AU  - Matsueda K
AD  - Department of Gastroenterology, National Hospital Organization Fukuyama Medical 
      Center, Japan.
FAU - Omote, Sizuma
AU  - Omote S
AD  - Department of Pathology, Okayama University Graduate School of Medicine, 
      Dentistry and Pharmaceutical Sciences, Japan.
FAU - Sakata, Masahiro
AU  - Sakata M
AD  - Department of Gastroenterology, National Hospital Organization Fukuyama Medical 
      Center, Japan.
FAU - Fujita, Isao
AU  - Fujita I
AD  - Department of Gastroenterology, National Hospital Organization Fukuyama Medical 
      Center, Japan.
FAU - Horii, Jouichiro
AU  - Horii J
AD  - Department of Gastroenterology, National Hospital Organization Fukuyama Medical 
      Center, Japan.
FAU - Toyokawa, Tatsuya
AU  - Toyokawa T
AD  - Department of Gastroenterology, National Hospital Organization Fukuyama Medical 
      Center, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20171221
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
SB  - IM
MH  - Aged
MH  - Biopsy
MH  - Diagnosis, Differential
MH  - Endoscopy
MH  - Flow Cytometry
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Lymphoma, B-Cell, Marginal Zone/*diagnosis/diagnostic imaging/pathology
MH  - Male
PMC - PMC5938496
OTO - NOTNLM
OT  - flow cytometry
OT  - fluorescence in situ hybridization
OT  - mucosa-associated lymphoid tissue lymphoma
OT  - reactive inflammatory lymphoid changes
OT  - trisomy 18
EDAT- 2017/12/23 06:00
MHDA- 2018/08/28 06:00
PMCR- 2018/04/15
CRDT- 2017/12/23 06:00
PHST- 2017/12/23 06:00 [pubmed]
PHST- 2018/08/28 06:00 [medline]
PHST- 2017/12/23 06:00 [entrez]
PHST- 2018/04/15 00:00 [pmc-release]
AID - 10.2169/internalmedicine.9617-17 [doi]
PST - ppublish
SO  - Intern Med. 2018 Apr 15;57(8):1081-1086. doi: 10.2169/internalmedicine.9617-17. 
      Epub 2017 Dec 21.