PMID- 29270037
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220311
IS  - 1179-5468 (Print)
IS  - 1179-5468 (Electronic)
IS  - 1179-5468 (Linking)
VI  - 11
DP  - 2017
TI  - Clinical and Echocardiographic Predictors of Arrhythmias Detected With 24-Hour 
      Holter Electrocardiography Among Hypertensive Heart Failure Patients in Nigeria.
PG  - 1179546817746632
LID - 10.1177/1179546817746632 [doi]
LID - 1179546817746632
AB  - BACKGROUND: Hypertensive heart failure (HHF) is the commonest form of heart 
      failure in Nigeria. There is paucity of data in Nigeria on 24-hour Holter 
      electrocardiography (24-HHECG) and important predictors of arrhythmias among HHF 
      patients. OBJECTIVES: To determine the 24-HHECG characteristics among HHF 
      patients. To determine the clinical and echocardiographic predictors of 
      arrhythmias detected using 24-HHECG among HHF patients. METHODS: A total of 100 
      HHF patients as well as 50 age-matched and sex-matched apparently healthy 
      controls were prospectively recruited over a period of 1 year. They all had 
      baseline laboratory tests, echocardiography, and 24-HHECG. RESULTS: Hypertensive 
      heart failure patients had significantly higher counts of premature ventricular 
      contractions (PVCs) than the controls (P </= .001). Ventricular tachycardia (VT) 
      was recorded in 29% of HHF patients as compared with controls who had no VT on 
      24-HHECG. The standard deviation of all normal to normal sinus RR intervals over 
      24 hours (SDNN) was abnormally reduced among HHF patients when compared with 
      controls (P = .046). There was positive correlation between atrial fibrillation 
      (AF) and the following parameters: PVCs (r = .229, P = .015), New York Heart 
      Association (NYHA) (r = .196, P = .033), and VT (r = .223, P = .018). Following 
      multiple linear regression, left ventricular ejection fraction (LVEF) (P </= .001) 
      and serum urea (P = .037) were predictors of PVCs among HHF patients. Serum 
      creatinine (P </= .001), elevated systolic blood pressure (SBP) (P = .005), and 
      PVCs (P </= .001) were important predictors of VT among HHF patients. CONCLUSIONS: 
      Renal dysfunction and reduced LVEF were important predictors of ventricular 
      arrhythmias. High counts of PVCs and elevated SBP were predictive of the 
      occurrence of VT among HHF patients. The NYHA class and ventricular arrhythmias 
      have a significant positive correlation with AF. The SDNN is reduced in HHF 
      patients.
FAU - Mene-Afejuku, Tuoyo Omasan
AU  - Mene-Afejuku TO
AD  - Department of Medicine, Metropolitan Hospital Center, New York, NY, USA.
FAU - Balogun, Michael Olabode
AU  - Balogun MO
AD  - Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching 
      Hospitals Complex, Ile-Ife, Nigeria.
FAU - Akintomide, Anthony Olubunmi
AU  - Akintomide AO
AD  - Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching 
      Hospitals Complex, Ile-Ife, Nigeria.
FAU - Adebayo, Rasaaq Ayodele
AU  - Adebayo RA
AD  - Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching 
      Hospitals Complex, Ile-Ife, Nigeria.
FAU - Ajayi, Olufemi Eyitayo
AU  - Ajayi OE
AD  - Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching 
      Hospitals Complex, Ile-Ife, Nigeria.
FAU - Amadi, Valentine N
AU  - Amadi VN
AD  - Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching 
      Hospitals Complex, Ile-Ife, Nigeria.
FAU - Oketona, Omolola Abiodun
AU  - Oketona OA
AD  - Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching 
      Hospitals Complex, Ile-Ife, Nigeria.
FAU - Ikwu, Amanze Nkemjika
AU  - Ikwu AN
AD  - Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching 
      Hospitals Complex, Ile-Ife, Nigeria.
FAU - Mene-Afejuku, Bamidele
AU  - Mene-Afejuku B
AD  - Faculty of Dentistry, Obafemi Awolowo University Teaching Hospitals Complex, 
      Ile-Ife, Nigeria.
FAU - Bamikole, Olaniyi James
AU  - Bamikole OJ
AD  - Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching 
      Hospitals Complex, Ile-Ife, Nigeria.
LA  - eng
PT  - Journal Article
DEP - 20171210
PL  - United States
TA  - Clin Med Insights Cardiol
JT  - Clinical Medicine Insights. Cardiology
JID - 101525768
PMC - PMC5731613
OTO - NOTNLM
OT  - Holter electrocardiography
OT  - atrial fibrillation
OT  - hypertensive heart failure
OT  - ventricular tachycardia
COIS- Declaration of conflicting interests:The author(s) declared no potential 
      conflicts of interest with respect to the research, authorship, and/or 
      publication of this article.
EDAT- 2017/12/23 06:00
MHDA- 2017/12/23 06:01
PMCR- 2017/12/10
CRDT- 2017/12/23 06:00
PHST- 2017/04/08 00:00 [received]
PHST- 2017/11/07 00:00 [accepted]
PHST- 2017/12/23 06:00 [entrez]
PHST- 2017/12/23 06:00 [pubmed]
PHST- 2017/12/23 06:01 [medline]
PHST- 2017/12/10 00:00 [pmc-release]
AID - 10.1177_1179546817746632 [pii]
AID - 10.1177/1179546817746632 [doi]
PST - epublish
SO  - Clin Med Insights Cardiol. 2017 Dec 10;11:1179546817746632. doi: 
      10.1177/1179546817746632. eCollection 2017.