PMID- 29274962
OWN - NLM
STAT- MEDLINE
DCOM- 20180816
LR  - 20181202
IS  - 1525-3198 (Electronic)
IS  - 0022-0302 (Linking)
VI  - 101
IP  - 3
DP  - 2018 Mar
TI  - Genetic parameters for body weight from birth to calving and associations between 
      weights with test-day, health, and female fertility traits.
PG  - 2158-2170
LID - S0022-0302(17)31194-3 [pii]
LID - 10.3168/jds.2017-13835 [doi]
AB  - A data set including 57,868 records for calf birth weight (CABW) and 9,462 
      records for weight at first insemination (IBW) were used for the estimation of 
      direct and maternal genetic effects in Holstein Friesian dairy cattle. 
      Furthermore, CABW and IBW were correlated with test-day production records and 
      health traits in first-lactation cows, and with nonreturn rates in heifers. 
      Health traits considered overall disease categories from the International 
      Committee for Animal Recording diagnosis key, including the general disease 
      status, diarrhea, respiratory diseases, mastitis, claw disorders, female 
      fertility disorders, and metabolic disorders. For single-trait measurements of 
      CABW and IBW, animal models with maternal genetic effects were applied. The 
      direct heritability was 0.47 for CABW and 0.20 for IBW, and the direct genetic 
      correlation between CABW and IBW was 0.31. A moderate maternal heritability 
      (0.19) was identified for CABW, but the maternal genetic effect was close to zero 
      for IBW. The correlation between direct and maternal genetic effects was 
      antagonistic for CABW (-0.39) and for IBW (-0.24). In bivariate animal models, 
      only weak genetic and phenotypic correlations were identified between CABW and 
      IBW with either test-day production or health traits in early lactation. Apart 
      from metabolic disorders, there was a general tendency for increasing disease 
      susceptibilities with increasing CABW. The genetic correlation between IBW and 
      nonreturn rates in heifers after 56 d and after 90 d was slightly positive 
      (0.18), but close to zero when correlating nonreturn rates with CABW. For the 
      longitudinal BW structure from birth to the age of 24 mo, random regression 
      models with the time-dependent covariate "age in months" were applied. Evaluation 
      criteria (Bayesian information criterion and residual variances) suggested 
      Legendre polynomials of order 3 to modeling the longitudinal body weight (BW) 
      structure. Direct heritabilities around birth and insemination dates were 
      slightly larger than estimates for CABW and IBW from the single-trait models, but 
      maternal heritabilities were exactly the same from both models. Genetic 
      correlations between BW were close to 1 for neighboring age classes, but 
      decreased with increasing time spans. The genetic correlation between BW at d 0 
      (birth date) and at 24 mo was even negative (-0.20). Random regression model 
      estimates confirmed the antagonistic relationship between direct and maternal 
      genetic effects, especially during calfhood. This study based on a large data set 
      in dairy cattle confirmed genetic parameters and (co)variance components for BW 
      as identified in beef cattle populations. However, BW records from an early stage 
      of life were inappropriate early predictors for dairy cow health and 
      productivity.
CI  - Copyright (c) 2018 American Dairy Science Association. Published by Elsevier Inc. 
      All rights reserved.
FAU - Yin, Tong
AU  - Yin T
AD  - Institute of Animal Breeding and Genetics, Justus-Liebig-University Giessen, 35390 
      Giessen, Germany.
FAU - Konig, Sven
AU  - Konig S
AD  - Institute of Animal Breeding and Genetics, Justus-Liebig-University Giessen, 35390 
      Giessen, Germany. Electronic address: sven.koenig@agrar.uni-giessen.de.
LA  - eng
PT  - Journal Article
DEP - 20171221
PL  - United States
TA  - J Dairy Sci
JT  - Journal of dairy science
JID - 2985126R
SB  - IM
MH  - Animals
MH  - Bayes Theorem
MH  - Birth Weight/*genetics
MH  - Body Weight/*genetics
MH  - Breeding
MH  - Cattle/*genetics
MH  - Female
MH  - Fertility/*genetics
MH  - *Health Status
MH  - Lactation/genetics
MH  - Models, Genetic
MH  - Parturition
MH  - Phenotype
MH  - Pregnancy
OTO - NOTNLM
OT  - body weight
OT  - genetic parameter
OT  - health and fertility trait
EDAT- 2017/12/25 06:00
MHDA- 2018/08/17 06:00
CRDT- 2017/12/25 06:00
PHST- 2017/09/14 00:00 [received]
PHST- 2017/11/01 00:00 [accepted]
PHST- 2017/12/25 06:00 [pubmed]
PHST- 2018/08/17 06:00 [medline]
PHST- 2017/12/25 06:00 [entrez]
AID - S0022-0302(17)31194-3 [pii]
AID - 10.3168/jds.2017-13835 [doi]
PST - ppublish
SO  - J Dairy Sci. 2018 Mar;101(3):2158-2170. doi: 10.3168/jds.2017-13835. Epub 2017 
      Dec 21.