PMID- 29275991
OWN - NLM
STAT- MEDLINE
DCOM- 20180529
LR  - 20180529
IS  - 1878-1551 (Electronic)
IS  - 1534-5807 (Linking)
VI  - 44
IP  - 1
DP  - 2018 Jan 8
TI  - Phytochrome A Negatively Regulates the Shade Avoidance Response by Increasing 
      Auxin/Indole Acidic Acid Protein Stability.
PG  - 29-41.e4
LID - S1534-5807(17)30952-8 [pii]
LID - 10.1016/j.devcel.2017.11.017 [doi]
AB  - The reduction in the red to far-red light ratio (R/FR) and photosynthetically 
      active radiation caused by dense planting initiates shade avoidance responses 
      (SARs) to help plants compete against their neighbors. However, deep shade 
      attenuates shade-induced stem elongation to suppress excessive reversion toward 
      skotomorphogenic development, in which photoreceptor phytochrome A (PHYA) has 
      been known to play the major role. However, the molecular mechanism underlying 
      PHYA function in deep shade is poorly understood. Here, we report that 
      shade-accumulated PHYA can release auxin/indole-3-acetic acid (AUX/IAA), 
      suppressors in the auxin signaling pathway, from SCF(TIR1), an auxin receptor, to 
      weaken auxin signaling and negatively regulate shade response. Corroborating 
      this, phyA mutants display an enhanced auxin response to deep shade and auxin 
      treatment. Specifically, PHYA competes with TIR1 by directly binding and 
      stabilizing AUX/IAA. Our findings illustrate a mechanistic model of how plants 
      sense different shade levels to fine-tune auxin signaling and generate 
      appropriate SAR.
CI  - Copyright (c) 2017 Elsevier Inc. All rights reserved.
FAU - Yang, Chuanwei
AU  - Yang C
AD  - State Key Laboratory of Genetic Engineering and Institute of Plant Biology, 
      School of Life Sciences, Fudan University, Shanghai 200438, People's Republic of 
      China.
FAU - Xie, Famin
AU  - Xie F
AD  - State Key Laboratory of Genetic Engineering and Institute of Plant Biology, 
      School of Life Sciences, Fudan University, Shanghai 200438, People's Republic of 
      China.
FAU - Jiang, Yupei
AU  - Jiang Y
AD  - State Key Laboratory of Genetic Engineering and Institute of Plant Biology, 
      School of Life Sciences, Fudan University, Shanghai 200438, People's Republic of 
      China.
FAU - Li, Zhen
AU  - Li Z
AD  - State Key Laboratory of Genetic Engineering and Institute of Plant Biology, 
      School of Life Sciences, Fudan University, Shanghai 200438, People's Republic of 
      China.
FAU - Huang, Xu
AU  - Huang X
AD  - State Key Laboratory of Genetic Engineering and Institute of Plant Biology, 
      School of Life Sciences, Fudan University, Shanghai 200438, People's Republic of 
      China.
FAU - Li, Lin
AU  - Li L
AD  - State Key Laboratory of Genetic Engineering and Institute of Plant Biology, 
      School of Life Sciences, Fudan University, Shanghai 200438, People's Republic of 
      China. Electronic address: linli@fudan.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20171221
PL  - United States
TA  - Dev Cell
JT  - Developmental cell
JID - 101120028
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (Indoleacetic Acids)
RN  - 0 (Phytochrome A)
RN  - 0 (Plant Growth Regulators)
RN  - 6U1S09C61L (indoleacetic acid)
SB  - IM
MH  - Arabidopsis/drug effects/growth & development/*metabolism
MH  - Arabidopsis Proteins/genetics/*metabolism
MH  - Gene Expression Regulation, Plant/*drug effects
MH  - Indoleacetic Acids/*pharmacology
MH  - *Light
MH  - Mutation
MH  - Phytochrome A/genetics/*metabolism
MH  - Plant Growth Regulators/pharmacology
MH  - Plant Physiological Phenomena
MH  - Plants, Genetically Modified/drug effects/growth & development/metabolism
MH  - Protein Stability/*drug effects
OTO - NOTNLM
OT  - AUX/IAA
OT  - auxin signaling
OT  - phytochrome A
OT  - protein stability
OT  - shade avoidance response
EDAT- 2017/12/26 06:00
MHDA- 2018/05/31 06:00
CRDT- 2017/12/26 06:00
PHST- 2017/03/08 00:00 [received]
PHST- 2017/08/15 00:00 [revised]
PHST- 2017/11/20 00:00 [accepted]
PHST- 2017/12/26 06:00 [pubmed]
PHST- 2018/05/31 06:00 [medline]
PHST- 2017/12/26 06:00 [entrez]
AID - S1534-5807(17)30952-8 [pii]
AID - 10.1016/j.devcel.2017.11.017 [doi]
PST - ppublish
SO  - Dev Cell. 2018 Jan 8;44(1):29-41.e4. doi: 10.1016/j.devcel.2017.11.017. Epub 2017 
      Dec 21.