PMID- 29276366 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1068-0640 (Print) IS - 1068-0640 (Linking) VI - 24 IP - 5 DP - 2017 Sep TI - Interstitial Pneumonia with Autoimmune Features: Overview of proposed criteria and recent cohort characterization. PG - 191-196 LID - 10.1097/CPM.0000000000000227 [doi] AB - The accurate diagnosis of interstitial lung disease (ILD) is essential for optimal prognostication and management. While connective tissue disease (CTD) is among the most common causes of ILD, some patients have features suggestive of autoimmunity without meeting criteria for a specific CTD. To help define and study this disease entity more uniformly, a 2015 research statement proposed consensus-based criteria and coined the term "interstitial pneumonia with autoimmune features" (IPAF). In this review, we summarize and compare previously proposed criteria to characterize these patients, provide an overview of the IPAF criteria and highlight recent investigations aimed at characterizing IPAF cohorts. We then call attention to questions that have arisen with the application of the IPAF criteria and discuss future areas of study. FAU - Lee, Cathryn T AU - Lee CT AD - Department of Medicine, Section of Pulmonary and Critical Care, University of Chicago, Chicago, IL. FAU - Oldham, Justin M AU - Oldham JM AD - Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of California, Davis, Sacramento, CA. LA - eng GR - KL2 TR001859/TR/NCATS NIH HHS/United States GR - UL1 TR001860/TR/NCATS NIH HHS/United States PT - Journal Article PL - United States TA - Clin Pulm Med JT - Clinical pulmonary medicine JID - 9421562 PMC - PMC5739083 MID - NIHMS895323 OTO - NOTNLM OT - connective tissue disease (CTD) OT - idiopathic pulmonary fibrosis (IPF) OT - interstitial lung disease (ILD) OT - interstitial pneumonia with autoimmune features (IPAF) COIS- Conflicts of Interest: None declared for Dr. Lee. Dr. Oldham has received speaking fees and sat on advisory boards for Genentech and Boehringer Ingelheim. EDAT- 2017/12/26 06:00 MHDA- 2017/12/26 06:01 PMCR- 2018/09/01 CRDT- 2017/12/26 06:00 PHST- 2017/12/26 06:00 [entrez] PHST- 2017/12/26 06:00 [pubmed] PHST- 2017/12/26 06:01 [medline] PHST- 2018/09/01 00:00 [pmc-release] AID - 10.1097/CPM.0000000000000227 [doi] PST - ppublish SO - Clin Pulm Med. 2017 Sep;24(5):191-196. doi: 10.1097/CPM.0000000000000227.